Biology and Therapeutic Potential of Mesenchymal Stem Cells derived Exosomes

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biologiayctma

Illuminating RNA Biology: Instruments for Imaging RNA in Stay Mammalian Cells

The central dogma teaches us that DNA makes RNA, which in flip makes proteins, the primary constructing blocks of the cell. However this over simplified linear transmission of data overlooks the overwhelming majority of the genome produces RNAs that don’t encode proteins and the myriad ways in which RNA regulates mobile features.

Traditionally, one of many challenges in illuminating RNA biology has been the shortage of instruments for visualizing RNA in dwell cells. However intelligent approaches for exploiting RNA binding proteins, in vitro RNA evolution, and chemical biology have resulted in vital advances in RNA visualization instruments lately. This evaluate offers an summary of present instruments for tagging RNA with fluorescent probes and monitoring their dynamics, localization andfunction in dwell mammalian cells.    

The Biology and Therapeutic Potential of Mesenchymal Stem Cells derived Exosomes

Mesenchymal stem cells (MSCs) are multipotent stromal cells with the potential to distinguish into a number of cell varieties. MSCs-based remedy has emerged as a promising technique for numerous ailments. Accumulating proof means that the paracrine results of MSCs are partially exerted by the secretion of soluble elements, particularly exosomes.

 MSC-derived exosomes are concerned within the intercellular communication through switch of proteins, RNA, DNA and bioactive lipids, which could represent a novel intercellular communication mode. This evaluate illustrates the present data on the composition, organic features, in addition to the therapeutic potential of MSC-derived exosomes in most cancers, with a concentrate on medical translation alternatives.  

biologiayctma
biologiayctma

Presenilin 1 antibody

70R-30727 100 ug
EUR 327
Description: Rabbit polyclonal Presenilin 1 antibody

Presenilin 1 Antibody

33474-100ul 100ul
EUR 252

Presenilin 1 Antibody

33474-50ul 50ul
EUR 187

Presenilin 1 Antibody

3481-100
EUR 338

Presenilin 1 antibody

20-PG71 100 ul
EUR 500
Description: Goat polyclonal Presenilin 1 antibody

Presenilin 1 antibody

70R-50277 100 ul
EUR 244
Description: Purified Polyclonal Presenilin 1 antibody

Presenilin 1 antibody

70R-6264 50 ug
EUR 467
Description: Rabbit polyclonal Presenilin 1 antibody raised against the N terminal of PSEN1

Presenilin 1 Antibody

AF0245 200ul
EUR 304
Description: Presenilin 1 antibody detects endogenous levels of total Presenilin 1.

Presenilin 1 Antibody

abx449128-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Presenilin 1 Antibody

ABF0245 100 ug
EUR 438

Goat Presenilin 1(PS 1) ELISA kit

E06P0869-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Presenilin 1(PS 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Presenilin 1(PS 1) ELISA kit

E06P0869-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Presenilin 1(PS 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Presenilin 1(PS 1) ELISA kit

E06P0869-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Presenilin 1(PS 1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Presenilin 1

GT15027 100 ug
EUR 526

Presenilin 1

RA18020 200 ul
EUR 483

Goat Presenilin 2 ELISA kit

E06P0149-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Presenilin 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Presenilin 2 ELISA kit

E06P0149-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Presenilin 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Presenilin 2 ELISA kit

E06P0149-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Presenilin 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Polyclonal Presenilin 1 Antibody

AMR09507G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Presenilin 1 . This antibody is tested and proven to work in the following applications:

Presenilin 1 (PSEN1) Antibody

20-abx008812
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Presenilin-1 (PSEN1) Antibody

abx022598-02ml 0.2 ml
EUR 509
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody

20-abx178082
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.

Presenilin 1 (PSEN1) Antibody

20-abx178083
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Presenilin 1 (PSEN1) Antibody

20-abx178084
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Presenilin 1 (PSEN1) Antibody

20-abx178085
  • EUR 1302.00
  • EUR 620.00
  • 1 mg
  • 200 ug
  • Please enquire.

Presenilin 1 (PSEN1) Antibody

20-abx114674
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody

20-abx174154
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Presenilin 1 (PSEN1) Antibody

20-abx174155
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug
  • Please enquire.

Presenilin 1 (PSEN1) Antibody

20-abx013181
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Presenilin 1 Conjugated Antibody

C33474 100ul
EUR 397

Presenilin 1 (PSEN1) Antibody

20-abx321554
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Presenilin-1-Specific Antibody

abx236769-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody

20-abx329062
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody

abx330584-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody

20-abx324712
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody

abx448576-100ug 100 ug
EUR 523
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (APC)

abx449138-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (Biotin)

abx449139-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (FITC)

abx449140-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (HRP)

abx449141-100ug 100 ug
EUR 592
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (PerCP)

abx449143-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (RPE)

abx449144-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (Streptavidin)

abx449145-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (Biotin)

abx446052-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (FITC)

abx446053-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (HRP)

abx446054-100ug 100 ug
EUR 565
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody

20-abx302486
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody

20-abx000533
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody

20-abx001799
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Presenilin 1 Polyclonal Antibody

ABP55848-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human Presenilin 1 around the non-phosphorylation site of S357
  • Applications tips:
Description: A polyclonal antibody for detection of Presenilin 1 from Human, Mouse, Rat. This Presenilin 1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Presenilin 1 around the non-phosphorylation site of S357

Presenilin 1 Polyclonal Antibody

ABP55848-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human Presenilin 1 around the non-phosphorylation site of S357
  • Applications tips:
Description: A polyclonal antibody for detection of Presenilin 1 from Human, Mouse, Rat. This Presenilin 1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Presenilin 1 around the non-phosphorylation site of S357

Presenilin 1 Polyclonal Antibody

ABP55848-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human Presenilin 1 around the non-phosphorylation site of S357
  • Applications tips:
Description: A polyclonal antibody for detection of Presenilin 1 from Human, Mouse, Rat. This Presenilin 1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Presenilin 1 around the non-phosphorylation site of S357

Presenilin 1 Polyclonal Antibody

ES6847-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Presenilin 1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Presenilin 1 Polyclonal Antibody

ES6847-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Presenilin 1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Anti-Presenilin 1 antibody

STJ95221 200 µl
EUR 197
Description: Rabbit polyclonal to Presenilin 1.

Goat Anti-Human Presenilin 1 (PS-1) antiserum # 3

PS13-S 100 ul
EUR 457

anti-Presenilin 1

YF-PA24492 50 ul
EUR 334
Description: Mouse polyclonal to Presenilin 1

Presenilin 1 Antibody (ATTO 390)

abx449129-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (ATTO 488)

abx449130-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (ATTO 565)

abx449131-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (ATTO 594)

abx449132-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (ATTO 633)

abx449133-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (ATTO 655)

abx449134-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (ATTO 680)

abx449135-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (ATTO 700)

abx449136-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 Antibody (Alkaline Phosphatase)

abx449137-100ug 100 ug
EUR 606
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody (ALP)

abx446050-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody (APC)

abx446051-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody (PerCP)

abx446056-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody (RPE)

abx446057-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody (Streptavidin)

abx446058-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Presenilin 1 (PSEN1) Antibody (HRP)

20-abx313028
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody (FITC)

20-abx313029
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) Antibody (Biotin)

20-abx313030
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Presenilin 1 (PSEN1) polyclonal antibody

ABP-PAB-11029 100 ug Ask for price
    • Product line: Miscellaneous
    • Brand:

anti- Presenilin-1-Specific antibody

FNab06769 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500-1:2000
  • Immunogen: presenilin 1
  • Uniprot ID: P49768
  • Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience
Description: Antibody raised against Presenilin-1-Specific

Anti-Presenilin-1-Specific antibody

PAab06769 100 ug
EUR 355

Antibody for Human Presenilin 1

SPC-734D 0.1mg
EUR 353
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is unconjugated.

Antibody for Human Presenilin 1

SPC-734D-A390 0.1mg
EUR 400
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 390.

Antibody for Human Presenilin 1

SPC-734D-A488 0.1mg
EUR 399
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 488.

Antibody for Human Presenilin 1

SPC-734D-A565 0.1mg
EUR 399
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 565.

Antibody for Human Presenilin 1

SPC-734D-A594 0.1mg
EUR 399
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 594.

Antibody for Human Presenilin 1

SPC-734D-A633 0.1mg
EUR 399
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 633.

Antibody for Human Presenilin 1

SPC-734D-A655 0.1mg
EUR 399
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 655.

Antibody for Human Presenilin 1

SPC-734D-A680 0.1mg
EUR 399
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 680.

Antibody for Human Presenilin 1

SPC-734D-A700 0.1mg
EUR 399
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to ATTO 700.

Antibody for Human Presenilin 1

SPC-734D-ALP 0.1mg
EUR 393
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human Presenilin 1

SPC-734D-APC 0.1mg
EUR 398
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to APC .

Antibody for Human Presenilin 1

SPC-734D-APCCY7 0.1mg
EUR 470
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to APC/Cy7.

Antibody for Human Presenilin 1

SPC-734D-BI 0.1mg
EUR 395
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to Biotin.

Antibody for Human Presenilin 1

SPC-734D-DY350 0.1mg
EUR 413
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to Dylight 350.

Antibody for Human Presenilin 1

SPC-734D-DY405 0.1mg
EUR 402
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to Dylight 405.

Antibody for Human Presenilin 1

SPC-734D-DY488 0.1mg
EUR 392
Description: A polyclonal antibody for Presenilin 1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic peptide of Human Presenilin 1 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).. The Antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000); IHC (1:50). This Presenilin 1 antibody is conjugated to Dylight 488.

The interface between coronaviruses and host cell RNA biology: Novel potential insights for future therapeutic intervention

Coronaviruses, together with SARS-Cov-2, are RNA-based pathogens that interface with a big number of RNA-related mobile processes throughout an infection. These processes embody capping, polyadenylation, localization, RNA stability, translation, and regulation by RNA binding proteins or noncoding RNA effectors. 

The aim of this text is to offer an in-depth perspective on the present state of information of how numerous coronaviruses work together with, usurp, and/or keep away from facets of those mobile RNA biology machineries. 

A radical understanding of how coronaviruses work together with RNA-related posttranscriptional processes within the cell ought to enable for brand new insights into facets of viral pathogenesis in addition to establish new potential avenues for the event of anti-coronaviral therapeutics. This text is categorized below: RNA in Illness and Improvement > RNA in Illness.   

Understanding the Biology of Human Interstitial Cells of Cajal in Gastrointestinal Motility

Thousands and thousands of sufferers worldwide endure from gastrointestinal (GI) motility problems comparable to gastroparesis. These problems sometimes embody debilitating signs, comparable to persistent nausea and vomiting. As no cures are at the moment out there, medical care is restricted to symptom administration, whereas the underlying causes of impaired GI motility stay unaddressed. The environment friendly motion of contents by means of the GI tract is facilitated by peristalsis. 

  • These rhythmic gradual waves of GI muscle contraction are mediated by a number of cell varieties, together with easy muscle cells, enteric neurons, telocytes, and specialised intestine pacemaker cells referred to as interstitial cells of Cajal (ICC).
  • As ICC dysfunction or loss has been implicated in a number of GI motility problems, ICC signify a probably invaluable therapeutic goal.
  • As a consequence of their availability, murine ICC have been extensively studied on the molecular stage utilizing each regular and diseased GI tissue. In distinction, comparatively little is thought in regards to the biology of human ICC or their involvement in GI illness pathogenesis.
  • Right here, we show human gastric tissue as a supply of major human cells with ICC phenotype.
  • Additional characterisation of those cells will present new insights into human GI biology, with the potential for creating novel therapies to handle the elemental causes of GI dysmotility.

Single cell genomics and developmental biology: shifting past the era of cell sort catalogues

Main developmental processes comparable to gastrulation and early embryogenesis depend on a posh community of cell-cell interactions, chromatin transforming, and transcriptional regulators.

This makes it difficult to review early improvement when utilizing bulk populations of cells. Latest advances in single-cell applied sciences have allowed researchers to higher perceive the interactions between completely different molecular modalities and the heterogeneities inside classically outlined cell varieties.  

As new single-cell applied sciences mature, they’ve the potential of offering a step-change in our understanding of embryogenesis. On this evaluate, we summarize current advances in single-cell applied sciences with specific concentrate on people who lend perception into early organogenesis. We then talk about present pitfalls and implications for future analysis. 

Monoclonal GR monoclonal antibody

AMM00029G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human GR monoclonal. The antibodies are raised in Mouse. This antibody is applicable in WB, FC, E, IP

Monoclonal EZH2 monoclonal antibody

AMM00030G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human EZH2 monoclonal. The antibodies are raised in Mouse.

Monoclonal HDAC2 monoclonal antibody

AMM00031G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human HDAC2 monoclonal. The antibodies are raised in Mouse. This antibody is applicable in WB and IF

Monoclonal ER alpha monoclonal antibody

AMM00027G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human ER alpha monoclonal. The antibodies are raised in Mouse. This antibody is applicable in WB, IC, E, IP, GS

Monoclonal ER alpha monoclonal antibody

AMM00028G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human ER alpha monoclonal. The antibodies are raised in Mouse. This antibody is applicable in WB

Monoclonal RbAp 46/48 monoclonal antibody

AMM00032G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human RbAp 46/48 monoclonal. The antibodies are raised in Mouse. This antibody is applicable in WB

Monoclonal RbAp 46/48 monoclonal antibody

AMM00033G 0.05mg
EUR 484
Description: A Monoclonal antibody against Human RbAp 46/48 monoclonal. The antibodies are raised in Mouse. This antibody is applicable in WB

Monoclonal CST3 Antibody (monoclonal), Clone: 1H4

AMM03425G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human CST3 (monoclonal). The antibodies are raised in Mouse and are from clone 1H4. This antibody is applicable in WB

Monoclonal TNFSF18 Antibody (monoclonal), Clone: 2E11

AMM04221G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human TNFSF18 (monoclonal). The antibodies are raised in mouse and are from clone 2E11. This antibody is applicable in WB, E

Monoclonal FTL Antibody (monoclonal), Clone: 4G7

AMM04622G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human FTL (monoclonal). The antibodies are raised in Mouse and are from clone 4G7. This antibody is applicable in WB, E

Anti-Dnmt3b Rabbit Monoclonal Antibody Rabbit Monoclonal Antibody

M00319 100ug/vial
EUR 397
Description: Rabbit Monoclonal Dnmt3b Antibody Antibody. Validated in IF, ICC, WB and tested in Human, Mouse, Rat.

VEGF Monoclonal Antibody

30217-100ul 100ul
EUR 252

VEGF Monoclonal Antibody

30217-50ul 50ul
EUR 187

BDNF Monoclonal Antibody

30320-100ul 100ul
EUR 252

BDNF Monoclonal Antibody

30320-50ul 50ul
EUR 187

CEACAM5 Monoclonal Antibody

30322-100ul 100ul
EUR 252

CEACAM5 Monoclonal Antibody

30322-50ul 50ul
EUR 187

TUBB3 Monoclonal Antibody

30323-100ul 100ul
EUR 252

TUBB3 Monoclonal Antibody

30323-50ul 50ul
EUR 187

RELA Monoclonal Antibody

30362-100ul 100ul
EUR 252

RELA Monoclonal Antibody

30362-50ul 50ul
EUR 187

AGK Monoclonal Antibody

29784-100ul 100ul
EUR 252

AGK Monoclonal Antibody

29784-50ul 50ul
EUR 187

MAP1LC3B Monoclonal Antibody

30037-100ul 100ul
EUR 252

MAP1LC3B Monoclonal Antibody

30037-50ul 50ul
EUR 187

Bad monoclonal Antibody

3005-100
EUR 338

Hemagglutinin Monoclonal Antibody

26005-100ul 100ul
EUR 390

Hemagglutinin Monoclonal Antibody

26006-100ul 100ul
EUR 390

Hemagglutinin Monoclonal Antibody

26007-100ul 100ul
EUR 390

Hemagglutinin Monoclonal Antibody

26008-100ul 100ul
EUR 390

Hemagglutinin Monoclonal Antibody

26009-100ul 100ul
EUR 390

PUMA Monoclonal Antibody

26010-100ul 100ul
EUR 390

PUMA Monoclonal Antibody

26011-100ul 100ul
EUR 390

PUMA Monoclonal Antibody

26012-100ul 100ul
EUR 390

PUMA Monoclonal Antibody

26013-100ul 100ul
EUR 390

EndoG Monoclonal Antibody

26014-100ul 100ul
EUR 390

EndoG Monoclonal Antibody

26015-100ul 100ul
EUR 390

EndoG Monoclonal Antibody

26016-100ul 100ul
EUR 390

EndoG Monoclonal Antibody

26017-100ul 100ul
EUR 390

Hemagglutinin Monoclonal Antibody

26018-100ul 100ul
EUR 390

Hemagglutinin Monoclonal Antibody

26019-100ul 100ul
EUR 390

MyD88 Monoclonal Antibody

26020-100ul 100ul
EUR 390

Hax1a Monoclonal Antibody

26021-100ul 100ul
EUR 390

Hax1a Monoclonal Antibody

26022-100ul 100ul
EUR 390

Hax1a Monoclonal Antibody

26023-100ul 100ul
EUR 390

Bim Monoclonal Antibody

26024-100ul 100ul
EUR 390

Bim Monoclonal Antibody

26025-100ul 100ul
EUR 390

ORAI3 Monoclonal Antibody

26028-100ul 100ul
EUR 390

ORAI3 Monoclonal Antibody

26029-100ul 100ul
EUR 390

CD4 Monoclonal Antibody

26036-100ul 100ul
EUR 390

CD4 Monoclonal Antibody

26037-100ul 100ul
EUR 390

ORAI1 Monoclonal Antibody

26038-100ul 100ul
EUR 390

ORAI1 Monoclonal Antibody

26039-100ul 100ul
EUR 390

IRAK Monoclonal Antibody

26040-100ul 100ul
EUR 390

IRAK Monoclonal Antibody

26041-100ul 100ul
EUR 390

KLF4 Monoclonal Antibody

26047-100ul 100ul
EUR 390

KLF4 Monoclonal Antibody

26048-100ul 100ul
EUR 390

JARID1C Monoclonal Antibody

27002-100ul 100ul
EUR 252

JARID1C Monoclonal Antibody

27002-50ul 50ul
EUR 187

TBL1Y Monoclonal Antibody

27006-100ul 100ul
EUR 252

TBL1Y Monoclonal Antibody

27006-50ul 50ul
EUR 187

TFIIB Monoclonal Antibody

27007-100ul 100ul
EUR 252

TFIIB Monoclonal Antibody

27007-50ul 50ul
EUR 187

KIAA1967 Monoclonal Antibody

27008-100ul 100ul
EUR 252

KIAA1967 Monoclonal Antibody

27008-50ul 50ul
EUR 187

HDAC4 Monoclonal Antibody

27009-100ul 100ul
EUR 252

HDAC4 Monoclonal Antibody

27009-50ul 50ul
EUR 187

CARM1 Monoclonal Antibody

27011-100ul 100ul
EUR 252

CARM1 Monoclonal Antibody

27011-50ul 50ul
EUR 187

CBX5 Monoclonal Antibody

27012-100ul 100ul
EUR 252

CBX5 Monoclonal Antibody

27012-50ul 50ul
EUR 187

NPM1 Monoclonal Antibody

27013-100ul 100ul
EUR 252

NPM1 Monoclonal Antibody

27013-50ul 50ul
EUR 187

POU5F1 Monoclonal Antibody

27014-100ul 100ul
EUR 252

POU5F1 Monoclonal Antibody

27014-50ul 50ul
EUR 187

SOX2 Monoclonal Antibody

27015-100ul 100ul
EUR 252

SOX2 Monoclonal Antibody

27015-50ul 50ul
EUR 187

PRMT6 Monoclonal Antibody

27017-100ul 100ul
EUR 252

PRMT6 Monoclonal Antibody

27017-50ul 50ul
EUR 187

P53 Monoclonal Antibody

27021-100ul 100ul
EUR 252

P53 Monoclonal Antibody

27021-50ul 50ul
EUR 187

TRIM28 Monoclonal Antibody

27026-100ul 100ul
EUR 252

TRIM28 Monoclonal Antibody

27026-50ul 50ul
EUR 187

EPCAM Monoclonal Antibody

27030-100ul 100ul
EUR 252

EPCAM Monoclonal Antibody

27030-50ul 50ul
EUR 187

TRIM33 Monoclonal Antibody

27032-100ul 100ul
EUR 252

TRIM33 Monoclonal Antibody

27032-50ul 50ul
EUR 187

CHD3 Monoclonal Antibody

27035-100ul 100ul
EUR 252

CHD3 Monoclonal Antibody

27035-50ul 50ul
EUR 187

TBLR1 Monoclonal Antibody

27036-100ul 100ul
EUR 252

TBLR1 Monoclonal Antibody

27036-50ul 50ul
EUR 187

Albumin Monoclonal Antibody

27044-100ul 100ul
EUR 252

Albumin Monoclonal Antibody

27044-50ul 50ul
EUR 187

DsbA Monoclonal Antibody

27049-100ul 100ul
EUR 252

DsbA Monoclonal Antibody

27049-50ul 50ul
EUR 187

FAS Monoclonal Antibody

27054-100ul 100ul
EUR 252

FAS Monoclonal Antibody

27054-50ul 50ul
EUR 187

ACE Monoclonal Antibody

27059-100ul 100ul
EUR 252

ACE Monoclonal Antibody

27059-50ul 50ul
EUR 187

FOXO1 Monoclonal Antibody

27063-100ul 100ul
EUR 252

FOXO1 Monoclonal Antibody

27063-50ul 50ul
EUR 187

CRTC1 Monoclonal Antibody

27071-100ul 100ul
EUR 252

CRTC1 Monoclonal Antibody

27071-50ul 50ul
EUR 187

CDC2 Monoclonal Antibody

27073-100ul 100ul
EUR 252

CDC2 Monoclonal Antibody

27073-50ul 50ul
EUR 187

HNRNPU Monoclonal Antibody

27076-100ul 100ul
EUR 252

HNRNPU Monoclonal Antibody

27076-50ul 50ul
EUR 187

ARRB1 Monoclonal Antibody

27077-100ul 100ul
EUR 252

ARRB1 Monoclonal Antibody

27077-50ul 50ul
EUR 187

KIF11 Monoclonal Antibody

27083-100ul 100ul
EUR 252

KIF11 Monoclonal Antibody

27083-50ul 50ul
EUR 187

SMYD2 Monoclonal Antibody

27084-100ul 100ul
EUR 252

SMYD2 Monoclonal Antibody

27084-50ul 50ul
EUR 187

PPP1CA Monoclonal Antibody

27087-100ul 100ul
EUR 252

PPP1CA Monoclonal Antibody

27087-50ul 50ul
EUR 187

SMYD1 Monoclonal Antibody

27088-100ul 100ul
EUR 252

SMYD1 Monoclonal Antibody

27088-50ul 50ul
EUR 187

Brgl Monoclonal Antibody

27090-100ul 100ul
EUR 252

Brgl Monoclonal Antibody

27090-50ul 50ul
EUR 187

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