Approaches to know cell biology and virulence of Entamoeba histolytica protozoan

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biologiayctma

Understanding the Mechanism of Cell Dying in Gemcitabine Resistant Pancreatic Ductal Adenocarcinoma: A Methods Biology Method

Background: Gemcitabine is the usual chemotherapeutic drug administered in superior Pancreatic Ductal Adenocarcinoma (PDAC). Nevertheless, on account of drug resistance in PDAC sufferers, this remedy has change into much less efficient.

Through the years, scientific trials for the search of discovering novel compounds that can be utilized together with gemcitabine have met little or no success.Goal: To foretell the driving elements behind pancreatic ductal adenocarcinoma, and to know the impact of those elements within the development of the illness and their contribution to cell progress and proliferation. 

Strategies: With the assistance of techniques biology approaches and utilizing gene expression knowledge, which is typically present in abundance, dysregulated components in key signalling pathways had been predicted. Distinguished dysregulated components had been built-in right into a mannequin to simulate and research the impact of gemcitabine-induced hypoxia.

 Outcomes: On this research, a number of transcription elements within the type of key drivers of cancer-related genes had been predicted with the assistance of CARNIVAL, and the impact of gemcitabine-induced hypoxia on the apoptosis pathway was proven to affect the downstream components of two main pathway fashions; EGF/VEGF and TNF signalling pathway. 

Conclusion: It was noticed that EGF/VEGF signalling pathway performed a serious function in inducing drug resistance by means of cell progress, proliferation, and avoiding cell loss of life. Focusing on the key upstream elements of this pathway might probably result in profitable remedy.Key phrases: PDAC; apoptosis; cell loss of life; cell signalling; gemcitabine; hypoxia; techniques biology.  

biologiayctma
biologiayctma

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Description: Rabbit anti Human IgG secondary antibody (FITC)

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Description: Rabbit anti Human IgG secondary antibody (Rhodamine)

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Description: Rabbit anti Human IgG secondary antibody (biotin)

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Description: Rabbit anti Human IgG secondary antibody (HRP)

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Description: Rabbit anti Human IgG secondary antibody (FITC)

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Description: Rabbit anti Human IgG secondary antibody (Rhodamine)

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Description: Rabbit anti Human IgG secondary antibody (biotin)

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Description: Rabbit anti Human IgG secondary antibody (HRP)

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Description: Rabbit anti Human IgG secondary antibody (FITC)

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Description: Rabbit anti Human IgG secondary antibody (Rhodamine)

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Description: Rabbit anti Human IgG secondary antibody (biotin)

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Description: Rabbit anti Human IgG secondary antibody (HRP)

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Description: Rabbit anti Human IgM secondary antibody (FITC)

Rabbit anti Human IgM (rhodamine)

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Description: Rabbit anti Human IgM secondary antibody (Rhodamine)

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Description: Rabbit anti Human IgM secondary antibody (biotin)

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Description: Rabbit anti Human IgM secondary antibody (HRP)

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Description: Rabbit anti Human IgA secondary antibody (FITC)

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Description: Rabbit anti Human IgA secondary antibody (Rhodamine)

Rabbit anti Human IgA (biotin)

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EUR 433.2
Description: Rabbit anti Human IgA secondary antibody (biotin)

Rabbit anti Human IgA (HRP)

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Description: Rabbit anti Human IgA secondary antibody (HRP)

Rabbit Anti-Human IgM Antibody

20-abx134798
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Anti-CD63 Antibody (rabbit anti-human) with goat anti-rabbit HRP secondary antibody

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Anti-CD81 Antibody (rabbit anti-human) with goat anti-rabbit HRP secondary antibody

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Anti-CD9 Antibody (rabbit anti-human) with goat anti-rabbit HRP secondary antibody

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Anti-Hsp70 Antibody (rabbit anti-human) with goat anti-rabbit HRP secondary antibody

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UltraTek Anti-Rabbit

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SensiTek Anti-Rabbit

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Rabbit anti Bovine

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Anti-Rabbit antibody

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Rabbit Anti-Human SMAD6 polyclonal antibody

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Rabbit Anti-Human GEN1 polyclonal antibody

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Rabbit Anti-Human STX8 polyclonal antibody

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Rabbit Anti-Human KIR3DL3 polyclonal antibody

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Rabbit Anti-Human PCDH15 polyclonal antibody

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Rabbit Anti-Human HGFAC polyclonal antibody

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Rabbit Anti-Human TXNL4A polyclonal antibody

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Rabbit Anti-Human PSMB1 polyclonal antibody

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Rabbit Anti-Human MYOC polyclonal antibody

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Rabbit Anti-Human IL12RB1 polyclonal antibody

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Rabbit Anti-Human TAPBP polyclonal antibody

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Rabbit Anti-Human DLGAP5 polyclonal antibody

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Rabbit Anti-Human HSPB2 polyclonal antibody

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Rabbit Anti-Human TCOF1 polyclonal antibody

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Rabbit Anti-Human NEDD9 polyclonal antibody

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Rabbit Anti-Human LRPAP1 polyclonal antibody

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Rabbit Anti-Human MMP25 polyclonal antibody

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Rabbit Anti-Human NTSR1 polyclonal antibody

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Rabbit Anti-Human UBC polyclonal antibody

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Rabbit Anti-Human LRPPRC polyclonal antibody

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Rabbit Anti-Human PTPN23 polyclonal antibody

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Rabbit Anti-Human LPCAT1 polyclonal antibody

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Rabbit Anti-Human SESN3 polyclonal antibody

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Rabbit Anti-Human DDX5 polyclonal antibody

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Rabbit Anti-Human POLD1 polyclonal antibody

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Rabbit Anti-Human KIF2C polyclonal antibody

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Rabbit Anti-Human SKIV2L2 polyclonal antibody

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Rabbit Anti-Human HADHB polyclonal antibody

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Rabbit Anti-Human DAPK1 polyclonal antibody

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Rabbit Anti-Human NFKBIB polyclonal antibody

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Rabbit Anti-Human HELLS polyclonal antibody

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Rabbit Anti-Human RBM3 polyclonal antibody

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Rabbit Anti-Human PRPF4 polyclonal antibody

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Rabbit Anti-Human CLPS polyclonal antibody

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Rabbit Anti-Human SLC26A2 polyclonal antibody

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Rabbit Anti-Human KIF2B polyclonal antibody

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Rabbit Anti-Human HPD polyclonal antibody

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Rabbit Anti-Human BAMBI polyclonal antibody

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Rabbit Anti-Human HUS1B polyclonal antibody

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Rabbit Anti-Human ANKRD28 polyclonal antibody

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Rabbit Anti-Human EME1 polyclonal antibody

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Rabbit Anti-Human UBE2NL polyclonal antibody

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Rabbit Anti-Human GTF2H4 polyclonal antibody

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Rabbit Anti-Human HRG polyclonal antibody

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Rabbit Anti-Human SLCO1A2 polyclonal antibody

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Rabbit Anti-Human FAM20A polyclonal antibody

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Rabbit Anti-Human PRDM11 polyclonal antibody

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Rabbit Anti-Human POLD4 polyclonal antibody

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Rabbit Anti-Human AQP9 polyclonal antibody

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Rabbit Anti-Human SLC16A11 polyclonal antibody

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Rabbit Anti-Human KCNK9 polyclonal antibody

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Rabbit Anti-Human CDY1 polyclonal antibody

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Rabbit Anti-Human BAZ1A polyclonal antibody

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EUR 702

Rabbit Anti-Human HIST1H2BG polyclonal antibody

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Rabbit Anti-Human GLDC polyclonal antibody

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EUR 702

Rabbit Anti-Human KIR3DS1 polyclonal antibody

CABT-BL111 100 ul
EUR 702

Rabbit Anti-Human TRIP12 polyclonal antibody

CABT-BL112 100 ul
EUR 702

Rabbit Anti-Human CLDND1 polyclonal antibody

CABT-BL120 100 ul
EUR 702

Rabbit Anti-Human RGN polyclonal antibody

CABT-BL121 100 ul
EUR 702

Rabbit Anti-Human UBL3 polyclonal antibody

CABT-BL122 100 ul
EUR 702

Rabbit Anti-Human KCNJ5 polyclonal antibody

CABT-BL123 100 ul
EUR 702

Rabbit Anti-Human CENPK polyclonal antibody

CABT-BL124 100 ul
EUR 702

Rabbit Anti-Human SERPINA12 polyclonal antibody

CABT-BL125 100 ul
EUR 702

Rabbit Anti-Human CNTNAP3 polyclonal antibody

CABT-BL126 100 ul
EUR 702

Rabbit Anti-Human EBNA1BP2 polyclonal antibody

CABT-BL127 100 ul
EUR 702

Rabbit Anti-Human RBM15B polyclonal antibody

CABT-BL128 100 ul
EUR 702

Rabbit Anti-Human DET1 polyclonal antibody

CABT-BL129 100 ul
EUR 702

Rabbit Anti-Human MZT2B polyclonal antibody

CABT-BL130 100 ul
EUR 702

Rabbit Anti-Human DIAPH2 polyclonal antibody

CABT-BL133 100 ul
EUR 702

Rabbit Anti-Human EVPL polyclonal antibody

CABT-BL134 100 ul
EUR 702

Rabbit Anti-Human XPNPEP2 polyclonal antibody

CABT-BL135 100 ul
EUR 702

Rabbit Anti-Human BICD2 polyclonal antibody

CABT-BL136 100 ul
EUR 702

Rabbit Anti-Human IL20RA polyclonal antibody

CABT-BL137 100 ul
EUR 702

Rabbit Anti-Human GNG2 polyclonal antibody

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EUR 702

Rabbit Anti-Human SLC28A3 polyclonal antibody

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EUR 702

Rabbit Anti-Human FCRL4 polyclonal antibody

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EUR 702

Rabbit Anti-Human L3MBTL2 polyclonal antibody

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EUR 702

Rabbit Anti-Human STRIP1 polyclonal antibody

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EUR 702

Rabbit Anti-Human SLC4A5 polyclonal antibody

CABT-BL143 100 ul
EUR 702

Rabbit Anti-Human JMJD8 polyclonal antibody

CABT-BL144 100 ul
EUR 702

Rabbit Anti-Human NOMO1 polyclonal antibody

CABT-BL145 100 ul
EUR 702

Rabbit Anti-Human CRP monoclonal antibody

CABT-BL8427 100 ul
EUR 795.6

Rabbit Anti-Human CRP monoclonal antibody

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EUR 795.6

Rabbit Anti-Human CRP monoclonal antibody

CABT-BL8429 100 ul
EUR 795.6

Rabbit Anti-Human CRP monoclonal antibody

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EUR 795.6

Rabbit Anti-Human Myoglobin monoclonal antibody

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EUR 795.6

Rabbit Anti-Human Myoglobin monoclonal antibody

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EUR 795.6

Rabbit Anti-Human Myoglobin monoclonal antibody

CABT-BL8434 100 ul
EUR 795.6

Rabbit Anti-Human Myoglobin monoclonal antibody

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EUR 795.6

Rabbit Anti-Human cTnI monoclonal antibody

CABT-BL8437 100 ul
EUR 795.6

Rabbit Anti-Human cTnI monoclonal antibody

CABT-BL8438 100 ul
EUR 795.6

Rabbit Anti-Human CKMB monoclonal antibody

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EUR 795.6

Rabbit Anti-Human CKMB monoclonal antibody

CABT-BL8440 100 ul
EUR 795.6

Rabbit Anti-Human ACTB monoclonal antibody

CABT-BL8441 100 ul
EUR 795.6

Rabbit Anti-Human ACTB monoclonal antibody

CABT-BL8442 100 ul
EUR 795.6

Rabbit Anti-Human FABP3 monoclonal antibody

CABT-BL8443 100 ul
EUR 795.6

Rabbit Anti-Human FABP3 monoclonal antibody

CABT-BL8444 100 ul
EUR 795.6

Proteomics approaches to know cell biology and virulence of Entamoeba histolytica protozoan parasite

  • Entamoeba histolytica is the primitive eukaryotic parasite accountable of human amoebiasis, a illness characterised by bloody intestinal diarrhea and invasive extraintestinal sickness.
  • The data of the full genome sequence of virulent E. histolytica and associated non-pathogenic species allowed the event of novel genome-wide methodological approaches together with protein expression profiling and mobile proteomics within the so referred to as post-genomic period.
  • Proteomics research have vastly elevated our understanding of the cell biology of this historic parasite.
  • This overview summarizes the present works regarding proteomics research on cell biology, life cycle, virulence and pathogenesis, novel therapies, and protein expression regulation mechanisms in E. histolytica parasite.
  • Additionally, we talk about using proteomics knowledge for the event of novel therapies, the identification of potential illness biomarkers and differential prognosis between species.
  • SIGNIFICANCE: Entamoeba histolytica is the unicellular protozoan parasite accountable of human amoebiasis, a critical illness with worldwide distribution characterised by bloody intestinal diarrhea and invasive extraintestinal sickness together with peritonitis and liver, pulmonary and mind abscesses.
  • The post-genomic period allowed the event of proteomic research together with protein expression profiling and mobile proteomics.
  • These proteomics research have vastly elevated our understanding on cell biology, life cycle (cyst-trophozoite conversion), virulence, pathogenesis, novel therapies, and protein expression regulation mechanisms in E. histolytica.
  • Importantly, proteomics has revealed the identification of proteins associated to novel therapies, and the identification of potential illness biomarkers and proteins with use in prognosis between species.
  • Hopefully within the coming years, and thru using extra subtle omics instruments, together with deep proteomics, a extra full set of proteins concerned within the aforementioned mobile processes might be obtained and thus perceive the biology of this historic eukaryote.

Useful Modules of Minimal Cell Division for Artificial Biology

Mobile replica is without doubt one of the basic hallmarks of life. Due to this fact, the event of a minimal division equipment able to correct genome condensation and group, mid-cell positioning and segregation in area and time, and the ultimate septation course of represent a basic challenge for artificial biology. It’s due to this fact vital to have the ability to engineer such modules for the manufacturing of synthetic minimal cells. 

A bottom-up meeting of molecular machines from bulk biochemicals complemented by in vivo experiments in addition to computational modelling helps to method such key mobile processes. Right here, minimal useful modules concerned in genome segregation and the division equipment and their spatial group and positioning are reviewed, setting into perspective the design of a minimal cell. Moreover, the milestones of latest in vitro reconstitution experiments within the context of cell division are mentioned and their function in shedding mild on basic mobile mechanisms that represent spatiotemporal order is described. Lastly, present challenges within the subject of bottom-up artificial biology in addition to potential future developments towards the event of minimal biomimetic techniques are mentioned. 

PRKCA Antibody

1-CSB-PA898666
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100

PRKCA Antibody

1-CSB-PA937356
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000

PRKCA Antibody

1-CSB-PA15859A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

PRKCA Antibody

1-CSB-PA030237
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

PRKCA Antibody

1-CSB-PA030238
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000

PRKCA Antibody

1-CSB-PA030239
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

PRKCA Antibody

1-CSB-PA105506
  • EUR 380.40
  • EUR 292.80
  • 100ul
  • 50ul
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

PRKCA Antibody

CSB-PA018699KA01HU-
EUR 402
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

PRKCA Antibody

CSB-PA018699KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

Mouse Prkca Antibody

abx027933-400ul 400 ul
EUR 627.6

Mouse Prkca Antibody

abx027933-80l 80 µl
EUR 343.2

PRKCA (pY658) Antibody

abx333503-100ul 100 ul
EUR 560.4

PRKCA (pT497) Antibody

abx217939-100ug 100 ug
EUR 526.8

PRKCA (pS657) Antibody

abx217940-100ug 100 ug
EUR 526.8

PRKCA Conjugated Antibody

C32053 100ul
EUR 476.4

Anti-PRKCA antibody

STJ112958 100 µl
EUR 548.4
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Anti-PRKCA antibody

STJ115305 100 µl
EUR 332.4
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Anti-PRKCA antibody

STJ25125 100 µl
EUR 332.4
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Prkca/ Rat Prkca ELISA Kit

ELI-04515r 96 Tests
EUR 1063.2

PRKCA siRNA

20-abx929759
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

PRKCA siRNA

20-abx929760
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

PRKCA (Phospho-Tyr195) Antibody

13096-100ul 100ul
EUR 302.4

PRKCA (Phospho-Tyr195) Antibody

13096-50ul 50ul
EUR 224.4

PRKCA (Phospho- Thr497) Antibody

ABF8395 100 ug
EUR 525.6

PRKCA (Phospho- Ser657) Antibody

ABF8396 100 ug
EUR 525.6

PRKCA (Ab-657) Antibody

CSB-PA589165-
EUR 402
Description: A polyclonal antibody against PRKCA (Ab-657). Recognizes PRKCA (Ab-657) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PRKCA (Ab-657) Antibody

CSB-PA589165-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against PRKCA (Ab-657). Recognizes PRKCA (Ab-657) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

Phospho-PRKCA (Tyr658) Antibody

CSB-PA060190-
EUR 402
Description: A polyclonal antibody against Phospho-PRKCA (Tyr658). Recognizes Phospho-PRKCA (Tyr658) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-PRKCA (Tyr658) Antibody

CSB-PA060190-100ul 100ul
EUR 434.4
Description: A polyclonal antibody against Phospho-PRKCA (Tyr658). Recognizes Phospho-PRKCA (Tyr658) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

PRKCA Antibody, HRP conjugated

1-CSB-PA15859B0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

PRKCA Antibody, FITC conjugated

1-CSB-PA15859C0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

PRKCA Antibody, Biotin conjugated

1-CSB-PA15859D0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against PRKCA. Recognizes PRKCA from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Phospho-PRKCA (Y657) Antibody

1-CSB-PA030235
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-PRKCA (Y657). Recognizes Phospho-PRKCA (Y657) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000

Phospho-PRKCA (T638) Antibody

1-CSB-PA030236
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-PRKCA (T638). Recognizes Phospho-PRKCA (T638) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

PRKCA Antibody / PKC alpha

F54688-0.08ML 0.08 ml
EUR 165

PRKCA Antibody / PKC alpha

F54688-0.4ML 0.4 ml
EUR 379

PRKCA Antibody / PKC alpha

F54980-0.08ML 0.08 ml
EUR 165

PRKCA Antibody / PKC alpha

F54980-0.4ML 0.4 ml
EUR 379

PRKCA Antibody / PKC alpha

F54061-0.1ML 0.1 ml
EUR 379

PRKCA Antibody / PKC alpha

V8687-100UG 100 ug
EUR 499
Description: Protein Kinase C alpha (PKC) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the isoform of PKC and binds to a sequence at the C terminus of PKC to detect its expression in vitro.

PRKCA Antibody / PKC alpha

V8687-20UG 20 ug
EUR 219
Description: Protein Kinase C alpha (PKC) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the isoform of PKC and binds to a sequence at the C terminus of PKC to detect its expression in vitro.

PRKCA Antibody / PKC alpha

V8687SAF-100UG 100 ug
EUR 499
Description: Protein Kinase C alpha (PKC) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the isoform of PKC and binds to a sequence at the C terminus of PKC to detect its expression in vitro.

PRKCA Rabbit pAb

A0267-100ul 100 ul
EUR 369.6

PRKCA Rabbit pAb

A0267-200ul 200 ul
EUR 550.8

PRKCA Rabbit pAb

A0267-20ul 20 ul
EUR 219.6

PRKCA Rabbit pAb

A0267-50ul 50 ul
EUR 267.6

PRKCA Rabbit pAb

A13342-100ul 100 ul
EUR 369.6

PRKCA Rabbit pAb

A13342-200ul 200 ul
EUR 550.8

PRKCA Rabbit pAb

A13342-20ul 20 ul
EUR 219.6

PRKCA Rabbit pAb

A13342-50ul 50 ul
EUR 267.6

PRKCA Rabbit mAb

A11107-100ul 100 ul
EUR 550.8

PRKCA Rabbit mAb

A11107-200ul 200 ul
EUR 823.2

PRKCA Rabbit mAb

A11107-20ul 20 ul Ask for price

PRKCA Rabbit mAb

A11107-50ul 50 ul
EUR 369.6

PRKCA Blocking Peptide

AF7740-BP 1mg
EUR 234

PRKCA Blocking Peptide

DF6070-BP 1mg
EUR 234

PRKCA cloning plasmid

CSB-CL018699HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the PRKCA gene.

Recombinant Human PRKCA

P0211 100ug
EUR 626.83
Description: Recombinant Human protein for PRKCA

PRKCA (Phospho-Tyr195) Conjugated Antibody

C13096 100ul
EUR 476.4

Anti-PKC alpha/PRKCA Antibody

PA1065 100ug/vial
EUR 400.8

Anti-PKC alpha/PRKCA Antibody

PB9318 100ug/vial
EUR 400.8

Anti-Phospho-PRKCA-(S226) antibody

STJ113497 100 µl
EUR 471.6
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Anti-Phospho-PRKCA-(S319) antibody

STJ117877 100 µl
EUR 471.6
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Protein Kinase C Alpha (PRKCA) Antibody

20-abx000652
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Kinase C Alpha (PRKCA) Antibody

20-abx125382
  • EUR 710.40
  • EUR 1028.40
  • EUR 493.20
  • 100 ul
  • 200 ul
  • 50 ul

Protein Kinase C Alpha (PRKCA) Antibody

abx116998-100ug 100 ug
EUR 560.4

Protein Interacting With Prkca 1 Antibody

20-abx114793
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Protein Kinase C Alpha (PRKCA) Antibody

abx034005-400ul 400 ul
EUR 627.6

Protein Kinase C Alpha (PRKCA) Antibody

abx034005-80l 80 µl
EUR 343.2

Protein Kinase C Alpha (PRKCA) Antibody

abx037155-100ug 100 ug
EUR 469.2

Protein kinase C alpha (PRKCA) Antibody

abx332517-100ul 100 ul
EUR 510

Protein kinase C alpha (PRKCA) Antibody

abx332239-100ul 100 ul
EUR 510

Protein kinase C alpha (PRKCA) Antibody

20-abx241740
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protein kinase C alpha (PRKCA) Antibody

20-abx241741
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protein kinase C alpha (PRKCA) Antibody

20-abx241990
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protein kinase C alpha (PRKCA) Antibody

20-abx242373
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Protein Kinase C Alpha (PRKCA) Antibody

20-abx302139
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein kinase C alpha (PRKCA) Antibody

20-abx326423
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Protein kinase C alpha (PRKCA) Antibody

20-abx327945
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Protein kinase C alpha (PRKCA) Antibody

20-abx329052
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Polyclonal Mouse Prkca Antibody (N-term)

APR03938G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mouse Prkca (N-term). This antibody is tested and proven to work in the following applications:

Anti-Phospho-PRKCA-S657/Y658 antibody

STJ11101090 100 µl
EUR 471.6
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Anti-Phospho-PRKCA/PRKCB-(T641) antibody

STJ22341 100 µl
EUR 471.6
Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Human PRKCA shRNA Plasmid

20-abx953748
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse PRKCA shRNA Plasmid

20-abx972057
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

PRKCA ELISA KIT|Human

EF005341 96 Tests
EUR 826.8

Human PRKCA ELISA Kit

ELA-E1380h 96 Tests
EUR 988.8

PRKCA Recombinant Protein (Rat)

RP222059 100 ug Ask for price

PRKCA Recombinant Protein (Human)

RP084903 100 ug Ask for price

PRKCA Recombinant Protein (Mouse)

RP164438 100 ug Ask for price

Protein Kinase C Alpha Type (PRKCA) Antibody

20-abx133286
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Protein Kinase C Alpha Type (PRKCA) Antibody

abx011355-100ug 100 ug
EUR 510

Protein Kinase C Alpha Type (PRKCA) Antibody

20-abx011394
  • EUR 526.80
  • EUR 309.60
  • EUR 92.40
  • 100 ug
  • 50 ug
  • 5 ug

Protein Kinase C Alpha Type (PRKCA) Antibody

20-abx012800
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Protein Kinase C Alpha Type (PRKCA) Antibody

abx033114-400ul 400 ul
EUR 627.6

Protein Kinase C Alpha Type (PRKCA) Antibody

abx033114-80l 80 µl
EUR 343.2

Phospho-threonine [T497] PKCalpha (PRKCA) polyclonal antibody

ABP-PAB-11667 100 ug Ask for price

Protein Kinase C Alpha (PRKCA) Antibody (HRP)

20-abx314446
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Kinase C Alpha (PRKCA) Antibody (FITC)

20-abx314447
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Kinase C Alpha (PRKCA) Antibody (Biotin)

20-abx314448
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Monoclonal PRKCA Antibody (monoclonal) (M01), Clone: 2F11

AMM03937G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human PRKCA (monoclonal) (M01). The antibodies are raised in mouse and are from clone 2F11. This antibody is applicable in WB, IHC and IF, E

Polyclonal PRKCA / PKC-Alpha Antibody (aa1-250)

APR03163G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PRKCA / PKC-Alpha (aa1-250). This antibody is tested and proven to work in the following applications:

Rabbit Anti-PRKCA monoclonal antibody, clone KG1075

DCABH-6947 100 ul
EUR 932.4

Phospho-PRKCA (Tyr195) Blocking Peptide

AF7240-BP 1mg
EUR 234

Phospho-PRKCA (Thr497) Blocking Peptide

AF8395-BP 1mg
EUR 234

Phospho-PRKCA (Ser657) Blocking Peptide

AF8396-BP 1mg
EUR 234

Human PRKCA-binding protein (PICK1)

1-CSB-RP054454h
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human PRKCA-binding protein(PICK1),partial expressed in E.coli

PRKCA ELISA Kit (Rat) (OKCA00995)

OKCA00995 96 Wells
EUR 1100.4
Description: Description of target: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signaling cascade, and/or by up-regulating CDKN1A, which facilitates active cyclin-dependent kinase (CDK) complex formation. In cells stimulated by the phorbol ester PMA, can trigger a cell cycle arrest program which is associated with the accumulation of the hyper-phosphorylated growth-suppressive form of RB1 and induction of the CDK inhibitors CDKN1A and CDKN1B. Depending on the cell type, exhibits anti-apoptotic function and protects cells from apoptosis by suppressing the p53/TP53-mediated activation of IGFBP3, or mediates anti-apoptotic action by phosphorylating BCL2. During macrophage differentiation induced by macrophage colony-stimulating factor (CSF1), is translocated to the nucleus and is associated with macrophage development. After wounding, translocates from focal contacts to lamellipodia and participates in the modulation of desmosomal adhesion. Plays a role in cell motility by phosphorylating CSPG4, which induces association of CSPG4 with extensive lamellipodia at the cell periphery and polarization of the cell accompanied by increases in cell motility. Negatively regulates myocardial contractility and positively regulates angiogenesis, platelet aggregation and thrombus formation in arteries. Mediates hypertrophic growth of neonatal cardiomyocytes, in part through a MAPK1/3 (ERK1/2)-dependent signaling pathway, and upon PMA treatment, is required to induce cardiomyocyte hypertrophy up to heart failure and death, by increasing protein synthesis, protein-DNA ratio and cell surface area. Regulates cardiomyocyte function by phosphorylating cardiac troponin T (TNNT2/CTNT), which induces significant reduction in actomyosin ATPase activity, myofilament calcium sensitivity and myocardial contractility. In angiogenesis, is required for full endothelial cell migration, adhesion to vitronectin (VTN), and vascular endothelial growth factor A (VEGFA)-dependent regulation of kinase activation and vascular tube formation. Involved in the stabilization of VEGFA mRNA at post-transcriptional level and mediates VEGFA-induced cell proliferation. In the regulation of calcium-induced platelet aggregation, mediates signals from the CD36/GP4 receptor for granule release, and activates the integrin heterodimer ITGA2B-ITGB3 through the RAP1GAP pathway for adhesion. During response to lipopolysaccharides (LPS), may regulate selective LPS-induced macrophage functions involved in host defense and inflammation. But in some inflammatory responses, may negatively regulate NF-kappa-B-induced genes, through IL1A-dependent induction of NF-kappa-B inhibitor alpha (NFKBIA/IKBA). Upon stimulation with 12-O-tetradecanoylphorbol-13-acetate (TPA), phosphorylates EIF4G1, which modulates EIF4G1 binding to MKNK1 and may be involved in the regulation of EIF4E phosphorylation. Phosphorylates KIT, leading to inhibition of KIT activity. Phosphorylates ATF2 which promotes cooperation between ATF2 and JUN, activating transcription.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 3.9 pg/mL

PRKCA ELISA Kit (Bovine) (OKEH06643)

OKEH06643 96 Wells
EUR 934.8
Description: Description of target: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signaling cascade, and/or by up-regulating CDKN1A, which facilitates active cyclin-dependent kinase (CDK) complex formation. In cells stimulated by the phorbol ester PMA, can trigger a cell cycle arrest program which is associated with the accumulation of the hyper-phosphorylated growth-suppressive form of RB1 and induction of the CDK inhibitors CDKN1A and CDKN1B. Depending on the cell type, exhibits anti-apoptotic function and protects cells from apoptosis by suppressing the p53/TP53-mediated activation of IGFBP3, or mediates anti-apoptotic action by phosphorylating BCL2. During macrophage differentiation induced by macrophage colony-stimulating factor (CSF1), is translocated to the nucleus and is associated with macrophage development. After wounding, translocates from focal contacts to lamellipodia and participates in the modulation of desmosomal adhesion. Plays a role in cell motility by phosphorylating CSPG4, which induces association of CSPG4 with extensive lamellipodia at the cell periphery and polarization of the cell accompanied by increases in cell motility. Negatively regulates myocardial contractility and positively regulates angiogenesis, platelet aggregation and thrombus formation in arteries. Mediates hypertrophic growth of neonatal cardiomyocytes, in part through a MAPK1/3 (ERK1/2)-dependent signaling pathway, and upon PMA treatment, is required to induce cardiomyocyte hypertrophy up to heart failure and death, by increasing protein synthesis, protein-DNA ratio and cell surface area. Regulates cardiomyocyte function by phosphorylating cardiac troponin T (TNNT2/CTNT), which induces significant reduction in actomyosin ATPase activity, myofilament calcium sensitivity and myocardial contractility. In angiogenesis, is required for full endothelial cell migration, adhesion to vitronectin (VTN), and vascular endothelial growth factor A (VEGFA)-dependent regulation of kinase activation and vascular tube formation. Involved in the stabilization of VEGFA mRNA at post-transcriptional level and mediates VEGFA-induced cell proliferation. In the regulation of calcium-induced platelet aggregation, mediates signals from the CD36/GP4 receptor for granule release, and activates the integrin heterodimer ITGA2B-ITGB3 through the RAP1GAP pathway for adhesion. During response to lipopolysaccharides (LPS), may regulate selective LPS-induced macrophage functions involved in host defense and inflammation. But in some inflammatory responses, may negatively regulate NF-kappa-B-induced genes, through IL1A-dependent induction of NF-kappa-B inhibitor alpha (NFKBIA/IKBA). Upon stimulation with 12-O-tetradecanoylphorbol-13-acetate (TPA), phosphorylates EIF4G1, which modulates EIF4G1 binding to MKNK1 and may be involved in the regulation of EIF4E phosphorylation. Phosphorylates KIT, leading to inhibition of KIT activity. Phosphorylates ATF2 which promotes cooperation between ATF2 and JUN, activating transcription.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 27 pg/mL

Prkca ELISA Kit (Rat) (OKEH04840)

OKEH04840 96 Wells
EUR 794.4
Description: Description of target: Displays Ca+2 dependent protein kinase activity;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.172 ng/mL

Prkca ELISA Kit (Mouse) (OKEH04841)

OKEH04841 96 Wells
EUR 794.4
Description: Description of target: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascades involving MAPK1/3 (ERK1/2) and RAP1GAP. Depending on the cell type, is involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signaling cascade, and/or by up-regulating CDKN1A, which facilitates active cyclin-dependent kinase (CDK) complex formation. In cells stimulated by the phorbol ester PMA, can trigger a cell cycle arrest program which is associated with the accumulation of the hyper-phosphorylated growth-suppressive form of RB1 and induction of the CDK inhibitors CDKN1A and CDKN1B. Depending on the cell type, exhibits anti-apoptotic function and protects cells from apoptosis by suppressing the p53/TP53-mediated activation of IGFBP3, or mediates anti-apoptotic action by phosphorylating BCL2. During macrophage differentiation induced by macrophage colony-stimulating factor (CSF1), is translocated to the nucleus and is associated with macrophage development. After wounding, translocates from focal contacts to lamellipodia and participates in the modulation of desmosomal adhesion. Plays a role in cell motility by phosphorylating CSPG4, which induces association of CSPG4 with extensive lamellipodia at the cell periphery and polarization of the cell accompanied by increases in cell motility. Negatively regulates myocardial contractility and positively regulates angiogenesis, platelet aggregation and thrombus formation in arteries. Mediates hypertrophic growth of neonatal cardiomyocytes, in part through a MAPK1/3 (ERK1/2)-dependent signaling pathway, and upon PMA treatment, is required to induce cardiomyocyte hypertrophy up to heart failure and death, by increasing protein synthesis, protein-DNA ratio and cell surface area. Regulates cardiomyocyte function by phosphorylating cardiac troponin T (TNNT2/CTNT), which induces significant reduction in actomyosin ATPase activity, myofilament calcium sensitivity and myocardial contractility. In angiogenesis, is required for full endothelial cell migration, adhesion to vitronectin (VTN), and vascular endothelial growth factor A (VEGFA)-dependent regulation of kinase activation and vascular tube formation. Involved in the stabilization of VEGFA mRNA at post-transcriptional level and mediates VEGFA-induced cell proliferation. In the regulation of calcium-induced platelet aggregation, mediates signals from the CD36/GP4 receptor for granule release, and activates the integrin heterodimer ITGA2B-ITGB3 through the RAP1GAP pathway for adhesion. During response to lipopolysaccharides (LPS), may regulate selective LPS-induced macrophage functions involved in host defense and inflammation. But in some inflammatory responses, may negatively regulate NF-kappa-B-induced genes, through IL1A-dependent induction of NF-kappa-B inhibitor alpha (NFKBIA/IKBA). Upon stimulation with 12-O-tetradecanoylphorbol-13-acetate (TPA), phosphorylates EIF4G1, which modulates EIF4G1 binding to MKNK1 and may be involved in the regulation of EIF4E phosphorylation. Phosphorylates KIT, leading to inhibition of KIT activity. Phosphorylates ATF2 which promotes cooperation between ATF2 and JUN, activating transcription.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.6 pg/mL

Prkca ORF Vector (Rat) (pORF)

ORF074021 1.0 ug DNA
EUR 607.2

PRKCA ORF Vector (Human) (pORF)

ORF028302 1.0 ug DNA
EUR 486

Prkca ORF Vector (Mouse) (pORF)

ORF054814 1.0 ug DNA
EUR 607.2

h PRKCA inducible lentiviral particles

LVP219 1x107 IFU/ml x 200ul
EUR 541.2
Description: Pre-made tet-inducible lentiviral particles expressing a human gene with a Blasticidin-RFP fusion marker (Dual selection). The expressed human gene, PRKCA, is fully sequence verified and matched to NCBI accession ID: NM_002737

PRKCA ELISA Kit (Human) (OKCD07796)

OKCD07796 96 Wells
EUR 1123.2
Description: Description of target: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 12.2pg/mL

PRKCA ELISA Kit (Mouse) (OKCD07797)

OKCD07797 96 Wells
EUR 981.6
Description: Description of target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab);Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.31ng/mL

PRKCA ELISA Kit (Rat) (OKCD07798)

OKCD07798 96 Wells
EUR 1201.2
Description: Description of target: Displays Ca+2 dependent protein kinase activity;Species reactivity: Rat;Application: ELISA;Assay info: ;Sensitivity: < 0.117ng/mL

PRKCA/PRKCB/PRKCD/PRKCE/PRKCH/PRKCQ Polyclonal Antibody

30229-100ul 100ul
EUR 302.4

PRKCA/PRKCB/PRKCD/PRKCE/PRKCH/PRKCQ Polyclonal Antibody

30229-50ul 50ul
EUR 224.4

Anti-PRKCA/PRKCB/PRKCD/PRKCE/PRKCH/PRKCQ antibody

STJ119908 100 µl
EUR 332.4

Phospho-PRKCA-S657/Y658 Rabbit pAb

AP0970-100ul 100 ul
EUR 460.8

Phospho-PRKCA-S657/Y658 Rabbit pAb

AP0970-200ul 200 ul
EUR 664.8

Phospho-PRKCA-S657/Y658 Rabbit pAb

AP0970-20ul 20 ul
EUR 219.6

Phospho-PRKCA-S657/Y658 Rabbit pAb

AP0970-50ul 50 ul
EUR 318

Prkca sgRNA CRISPR Lentivector set (Rat)

K6807301 3 x 1.0 ug
EUR 406.8

PRKCA sgRNA CRISPR Lentivector set (Human)

K1721501 3 x 1.0 ug
EUR 406.8

PRKCA sgRNA CRISPR Lentivector set (Human)

K0003901 3 x 1.0 ug
EUR 406.8

Prkca sgRNA CRISPR Lentivector set (Mouse)

K4855101 3 x 1.0 ug
EUR 406.8

PRKCA / PRKCB / PRKCD / PRKCE / PRKCG / PRKCH / PRKCQ / PRKCZ Antibody

20-abx329612
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

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