Biology hyperlinks temporal protein adjustments to drug responses in a melanoma cell

0 Comments
biologiayctma

CCR2 of Tumor Microenvironmental Cells Is a Related Modulator of Glioma Biology

 Glioblastoma multiforme (GBM) reveals a excessive inflow of tumor-associated macrophages (TAMs). The CCR2/CCL2 pathway is taken into account a related sign for the recruitment of TAMs and has been urged as a therapeutic goal in malignant gliomas. We discovered that TAMs of human GBM specimens and of a syngeneic glioma mannequin specific CCR2 to various extents. 

Utilizing a Ccr2-deficient pressure for glioma inoculation revealed a 30% discount of TAMs intratumorally. This diminished immune cell infiltration occurred with augmented tumor volumes probably based mostly on elevated cell proliferation. Remaining TAMs in Ccr2-/- mice confirmed comparable floor marker expression patterns compared to wildtype mice, however expression ranges of inflammatory transcription components (Stat3Irf7Cox2) and cytokines (IfnβIl1βIl12α) had been significantly affected. 

Moreover, we demonstrated an impression on blood vessel integrity, whereas vascularization of tumors appeared related between mouse strains. The upper stability and attenuated leakiness of the tumor vasculature indicate improved sustenance of glioma tissue in Ccr2-/- mice. Moreover, regardless of TAMs residing within the perivascular area of interest in Ccr2-/- mice, their pro-angiogenic exercise was decreased by the downregulation of Vegf. In conclusion, missing CCR2 solely on tumor microenvironmental cells results in enhanced tumor development, whereby excessive numbers of TAMs infiltrate gliomas independently of the CCR2/CCL2 sign.

Perturbation biology hyperlinks temporal protein adjustments to drug responses in a melanoma cell line

Most cancers cells have genetic alterations that always immediately have an effect on intracellular protein signaling processes permitting them to bypass management mechanisms for cell dying, development and division. Most cancers medication focusing on these alterations usually work initially, however resistance is widespread. Combos of focused medication could overcome or forestall resistance, however their choice requires context-specific information of signaling pathways together with complicated interactions resembling suggestions loops and crosstalk.

To deduce quantitative pathway fashions, we collected a wealthy dataset on a melanoma cell line: Following perturbation with 54 drug combos, we measured 124 (phospho-)protein ranges and phenotypic response (cell development, apoptosis) in a time sequence from 10 minutes to 67 hours.

 From these knowledge, we educated time-resolved mathematical fashions that seize molecular interactions and the coupling of molecular ranges to mobile phenotype, which in flip reveal the primary direct or oblique molecular responses to every drug. Systematic mannequin simulations recognized novel combos of medication predicted to cut back the survival of melanoma cells, with partial experimental verification. This specific software of perturbation biology demonstrates the potential impression of mixing time-resolved knowledge with modeling for the invention of recent combos of most cancers medication. 

biologiayctma
biologiayctma

Rat Beta-1 adrenergic receptor,ADRB1 ELISA KIT

E1882Ra-1096T 10*96T
EUR 4122

Rat Beta-1 adrenergic receptor,ADRB1 ELISA KIT

E1882Ra-48wells 48 wells
EUR 300

Rat Beta-1 adrenergic receptor,ADRB1 ELISA KIT

E1882Ra-596T 5*96T
EUR 2061

Rat Beta-1 adrenergic receptor,ADRB1 ELISA KIT

E1882Ra-96wells 96 wells
EUR 458

Rat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

RK14158 96T
EUR 280

Rat Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

abx155155-100g 100 µg
EUR 3275

Rat Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

abx155155-50g 50 µg
EUR 687.5

Rat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS7251359-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS7251359-48StripWells 48-Strip-Wells
EUR 485

Rat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS7251359-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS7251359-96StripWells 96-Strip-Wells
EUR 690

Rat Beta-1 adrenergic receptor, ADRB1 ELISA Kit

MBS1604663-10x96StripWells 10x96-Strip-Wells
EUR 3955

Rat Beta-1 adrenergic receptor, ADRB1 ELISA Kit

MBS1604663-48StripWells 48-Strip-Wells
EUR 305

Rat Beta-1 adrenergic receptor, ADRB1 ELISA Kit

MBS1604663-5x96StripWells 5x96-Strip-Wells
EUR 2005

Rat Beta-1 adrenergic receptor, ADRB1 ELISA Kit

MBS1604663-96StripWells 96-Strip-Wells
EUR 475

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Ra 96T
EUR 499
Description: tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Ra-48T 48T
EUR 658.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Ra-96T 96T
EUR 861.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43280-48T 48T
EUR 410.83

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43280-5x96T 5x96T
EUR 2787.78

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43280-96T 96T
EUR 586.9

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02169-48T 48T
EUR 603.26

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02169-5x96T 5x96T
EUR 4093.55

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02169-96T 96T
EUR 861.8

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DL-ADRb1-Ra 96T
EUR 475
Description: tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EK12482 96Т
EUR 768

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-48T 48T
EUR 487.7
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-48Tests 48 Tests
EUR 668.4

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-96T 96T
EUR 696.7
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-96Tests 96 Tests
EUR 930

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-48T 48T
EUR 512.09
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-48Tests 48 Tests
EUR 699.6

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-96T 96T
EUR 731.54
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-96Tests 96 Tests
EUR 973.2

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-10x96wellstestplate 10x96-wells test plate
EUR 6149.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-1x48wellstestplate 1x48-wells test plate
EUR 611.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-1x96wellstestplate 1x96-wells test plate
EUR 822.24
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-5x96wellstestplate 5x96-wells test plate
EUR 3340.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

4-SEC924Ra
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2023691-10x96StripWells 10x96-Strip-Wells
EUR 5705

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2023691-24StripWells 24-Strip-Wells
EUR 380

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2023691-48StripWells 48-Strip-Wells
EUR 575

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2023691-5x96StripWells 5x96-Strip-Wells
EUR 3125

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2023691-96StripWells 96-Strip-Wells
EUR 775

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS457442-10x96Tests 10x96Tests
EUR 5615

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS457442-48Tests 48Tests
EUR 485

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS457442-5x96Tests 5x96Tests
EUR 2875

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS457442-96Tests 96Tests
EUR 645

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS454882-10x96StripWells 10x96-Strip-Wells
EUR 5375

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS454882-48StripWells 48-Strip-Wells
EUR 470

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS454882-5x96StripWells 5x96-Strip-Wells
EUR 2760

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS454882-96StripWells 96-Strip-Wells
EUR 620

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2704798-10x96StripWells 10x96-Strip-Wells
EUR 3390

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2704798-24StripWells 24-Strip-Wells
EUR 260

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2704798-48StripWells 48-Strip-Wells
EUR 350

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2704798-5x96StripWells 5x96-Strip-Wells
EUR 1760

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

MBS2704798-96StripWells 96-Strip-Wells
EUR 445

Rat Adrb1/ Beta-1 adrenergic receptor ELISA Kit

E0033Ra 1 Kit
EUR 557
Description: Adrb1r,Beta-1 adrenoreceptor,Beta-1 adrenoceptor

Rat Adrb1 / Beta-1 adrenergic receptor ELISA Kit

E10653r 96T
EUR 796

Rat ADRb1(Adrenergic Receptor Beta 1) ELISA Kit

ELK7002-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADRb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADRb1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat ADRb1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat ADRb1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat ADRb1(Adrenergic Receptor Beta 1) ELISA Kit

ELK7002-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADRb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADRb1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat ADRb1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat ADRb1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat ADRb1(Adrenergic Receptor Beta 1) ELISA Kit

ER0719 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 46.875pg/ml

Rat Adrenergic Receptor Beta 1 ELISA Kit (ADRb1)

RK03473 96 Tests
EUR 625.2

Rat ADRb1 (Adrenergic Receptor Beta 1) ELISA Kit

MBS8805979-10x96StripWells 10x96-Strip-Wells
EUR 3130

Rat ADRb1 (Adrenergic Receptor Beta 1) ELISA Kit

MBS8805979-48StripWells 48-Strip-Wells
EUR 350

Rat ADRb1 (Adrenergic Receptor Beta 1) ELISA Kit

MBS8805979-5x96StripWells 5x96-Strip-Wells
EUR 1710

Rat ADRb1 (Adrenergic Receptor Beta 1) ELISA Kit

MBS8805979-96StripWells 96-Strip-Wells
EUR 445

Rat ADRb1(Adrenergic Receptor Beta 1)ELISA Kit

MBS2515671-10x96Tests 10x96Tests
EUR 4060

Rat ADRb1(Adrenergic Receptor Beta 1)ELISA Kit

MBS2515671-24Tests 24Tests
EUR 265

Rat ADRb1(Adrenergic Receptor Beta 1)ELISA Kit

MBS2515671-48Test 48Test
EUR 450

Rat ADRb1(Adrenergic Receptor Beta 1)ELISA Kit

MBS2515671-5x96Test 5x96Test
EUR 2265

Rat ADRb1(Adrenergic Receptor Beta 1)ELISA Kit

MBS2515671-96Tests 96Tests
EUR 535

ELISA kit for Rat Beta-1 adrenergic receptor (ADRB1)

KTE100346-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Rat Beta-1 adrenergic receptor (ADRB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Beta-1 adrenergic receptor (ADRB1)

KTE100346-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Rat Beta-1 adrenergic receptor (ADRB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Beta-1 adrenergic receptor (ADRB1)

KTE100346-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Rat Beta-1 adrenergic receptor (ADRB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat ADRb1 (Adrenergic Receptor Beta 1)

ELK7002 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Adrenergic Receptor Beta 1 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Rat Beta-1 adrenergic Receptor, ADRB1 GENLISA ELISA

KLR1882 1 x 96 wells
EUR 341

Cow Beta-1 adrenergic receptor (ADRB1) ELISA Kit

abx515005-96tests 96 tests
EUR 1093.2

Dog Beta-1 adrenergic receptor (ADRB1) ELISA Kit

abx515006-96tests 96 tests
EUR 1093.2

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

abx515009-96tests 96 tests
EUR 1093.2

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24101PI-48Tests 48 Tests
EUR 360
Description: Pig (Sus scrofa; Porcine)

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24101PI-96Tests 96 Tests
EUR 680
Description: Pig (Sus scrofa; Porcine)

Cat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24096CA-48T 48T
EUR 360
Description: Cat (Felis catus,Feline)

Cat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24096CA-96T 96T
EUR 680
Description: Cat (Felis catus,Feline)

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24101PI-48T 48T
EUR 360
Description: Pig (Sus scrofa; Porcine)

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24101PI-96T 96T
EUR 680
Description: Pig (Sus scrofa; Porcine)

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

RK14988 96T
EUR 280

Cat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS285982-10x96StripWells 10x96-Strip-Wells
EUR 6840

Cat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS285982-48StripWells 48-Strip-Wells
EUR 480

Cat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS285982-5x96StripWells 5x96-Strip-Wells
EUR 3610

Cat Beta-1 adrenergic receptor (ADRB1) ELISA Kit

MBS285982-96StripWells 96-Strip-Wells
EUR 805

Mouse Beta- 1 adrenergic receptor, Adrb1 ELISA KIT

ELI-24563m 96tests
EUR 736

Human beta 1 adrenergic receptor (ADRB1) ELISA Kit

MBS7215839-10x96StripWells 10x96-Strip-Wells
EUR 5685

On the leading edge: protease-based strategies for sensing and controlling cell biology

Sequence-specific proteases have confirmed to be versatile constructing blocks for instruments that report or management mobile perform. Reporting strategies hyperlink protease exercise to biochemical alerts, whereas management strategies depend on engineering proteases to reply to exogenous inputs resembling gentle or chemical substances.

 In flip, proteases have inherent management skills, as their native features are to launch, activate or destroy proteins by cleavage, with the irreversibility of proteolysis permitting sustained downstream results. In consequence, protease-based artificial circuits have been created for various makes use of resembling reporting mobile signaling, tuning protein expression, controlling viral replication and detecting most cancers states. Right here, we comprehensively evaluate the event and software of protease-based strategies for reporting and controlling mobile perform in eukaryotes. 

Cytochrome C Antibody

21680 100ul
EUR 319

Cytochrome C Antibody

21680-100ul 100ul
EUR 302.4

Cytochrome C Antibody

21680-50ul 50ul
EUR 224.4

Cytochrome c antibody

20R-1430 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

20R-1518 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

20R-1519 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c Antibody

3025-100 each
EUR 438

Cytochrome c Antibody

3025-30T each
EUR 175.2

Cytochrome c Antibody

33354 100ul
EUR 319

Cytochrome c Antibody

33354-100ul 100ul
EUR 302.4

Cytochrome c Antibody

33354-50ul 50ul
EUR 224.4

Cytochrome c Antibody

3352-100 each
EUR 379.2

Cytochrome c Antibody

3352-30T each
EUR 175.2

Cytochrome c Antibody

3353-100 each
EUR 379.2

Cytochrome c Antibody

3353-30T each
EUR 175.2

Cytochrome C Antibody

48927 100ul
EUR 499

Cytochrome C Antibody

48927-100ul 100ul
EUR 399.6

Cytochrome C Antibody

48927-50ul 50ul
EUR 286.8

Cytochrome C Antibody

48976 100ul
EUR 499

Cytochrome C Antibody

48976-100ul 100ul
EUR 399.6

Cytochrome C Antibody

48976-50ul 50ul
EUR 286.8

Cytochrome c Antibody

E033354 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cytochrome C Antibody

E021680 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cytochrome c Antibody

E11-0170C 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-0146-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-0146-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-7004-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-7004-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome C Antibody

DF6028 200ul
EUR 420

Cytochrome C Antibody

DF6028-100ul 100ul
EUR 280

Cytochrome C Antibody

DF6028-200ul 200ul
EUR 350

Cytochrome c Antibody

E38PA6018 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E38PA9145 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E38PA2689 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome C antibody

BF0714 200ul
EUR 540

Cytochrome C antibody

BF0714-100ul 100ul
EUR 350

Cytochrome C antibody

BF0714-200ul 200ul
EUR 450

Cytochrome C antibody

BF0714-50ul 50ul
EUR 250

Cytochrome c antibody

70R-13781 100 ug
EUR 519
Description: Affinity purified Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11564 100 ug
EUR 406
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11766 100 ug
EUR 343
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11767 100 ug
EUR 343
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome C antibody

70R-31158 100 ug
EUR 294
Description: Rabbit polyclonal Cytochrome C antibody

Cytochrome C antibody

70R-51008 100 ul
EUR 242
Description: Purified Polyclonal Cytochrome C antibody

Cytochrome C Antibody

AF0146 200ul
EUR 420

Cytochrome C Antibody

AF0146-100ul 100ul
EUR 280

Cytochrome C Antibody

AF0146-200ul 200ul
EUR 350

Cytochrome C Antibody

AF7004 200ul
EUR 540

Cytochrome C Antibody

AF7004-100ul 100ul
EUR 350

Cytochrome C Antibody

AF7004-200ul 200ul
EUR 450

Cytochrome C Antibody

AF7004-50ul 50ul
EUR 250

Cytochrome c Antibody

ABF0146 100ug
EUR 325

Cytochrome c Antibody

ABF7004 100ug
EUR 325

Cytochrome C Antibody

GWB-56035A 0.1 mg Ask for price

Cytochrome C, Antibody

GWB-5AC847 1 ml Ask for price

Cytochrome C, Antibody

GWB-83C84A 7 ml Ask for price

Cytochrome C Antibody

GWB-F62EAD 0.1 mg Ask for price

Cytochrome C Antibody

GWB-CE42EA 0.05 mg Ask for price

Cytochrome C Antibody

R32947 100 ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

R31747 100 ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

RQ4499 100ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

V8015-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8015-20UG 20 ug
EUR 153.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8015SAF-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358-20UG 20 ug
EUR 153.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358SAF-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2785-100UG 100 ug
EUR 424.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2785-20UG 20 ug
EUR 186.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2785SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2786-100UG 100 ug
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786-20UG 20 ug
EUR 186.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786IHC-7ML 7 ml
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786SAF-100UG 100 ug
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2788-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2789-100UG 100 ug
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789-20UG 20 ug
EUR 186.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome c Antibody

MBS7138755-INQUIRE INQUIRE Ask for price

Cytochrome c Antibody

MBS7138757-INQUIRE INQUIRE Ask for price

Cytochrome c Antibody

MBS7138758-INQUIRE INQUIRE Ask for price

Cytochrome c Antibody

MBS7138760-INQUIRE INQUIRE Ask for price

Cytochrome c Antibody

MBS7138762-INQUIRE INQUIRE Ask for price

Cytochrome c Antibody

MBS9412376-005mL 0.05mL
EUR 245

Cytochrome c Antibody

MBS9412376-01mL 0.1mL
EUR 305

Cytochrome c Antibody

MBS9412376-5x01mL 5x0.1mL
EUR 1230

Cytochrome C Antibody

MBS9409878-005mL 0.05mL
EUR 245

Cytochrome C Antibody

MBS9409878-01mL 0.1mL
EUR 305

Cytochrome C Antibody

MBS9409878-5x01mL 5x0.1mL
EUR 1230

Cytochrome c Antibody

MBS8584316-01mL 0.1mL
EUR 305

Cytochrome c Antibody

MBS8584316-01mLAF405L 0.1mL(AF405L)
EUR 465

Cytochrome c Antibody

MBS8584316-01mLAF405S 0.1mL(AF405S)
EUR 465

Cytochrome c Antibody

MBS8584316-01mLAF610 0.1mL(AF610)
EUR 465

Cytochrome c Antibody

MBS8584316-01mLAF635 0.1mL(AF635)
EUR 465

Cytochrome c Antibody

MBS8583707-01mL 0.1mL
EUR 305

Cytochrome c Antibody

MBS8583707-01mLAF405L 0.1mL(AF405L)
EUR 465

Cytochrome c Antibody

MBS8583707-01mLAF405S 0.1mL(AF405S)
EUR 465

Cytochrome c Antibody

MBS8583707-01mLAF610 0.1mL(AF610)
EUR 465

Cytochrome c Antibody

MBS8583707-01mLAF635 0.1mL(AF635)
EUR 465

Cytochrome c Antibody

MBS9201868-01mL 0.1mL
EUR 425

Cytochrome c Antibody

MBS9201868-5x01mL 5x0.1mL
EUR 1887

Cytochrome c Antibody

MBS8581490-01mL 0.1mL
EUR 305

Cytochrome c Antibody

MBS8581490-01mLAF405L 0.1mL(AF405L)
EUR 465

Cytochrome c Antibody

MBS8581490-01mLAF405S 0.1mL(AF405S)
EUR 465

Cytochrome c Antibody

MBS8581490-01mLAF610 0.1mL(AF610)
EUR 465

Cytochrome c Antibody

MBS8581490-01mLAF635 0.1mL(AF635)
EUR 465

Cytochrome c Antibody

MBS853572-01mg 0.1mg
EUR 305

Cytochrome c Antibody

MBS853572-01mLAF405L 0.1mL(AF405L)
EUR 465

Cytochrome c Antibody

MBS853572-01mLAF405S 0.1mL(AF405S)
EUR 465

Cytochrome c Antibody

MBS853572-01mLAF610 0.1mL(AF610)
EUR 465

Cytochrome c Antibody

MBS853572-01mLAF635 0.1mL(AF635)
EUR 465

Cytochrome c Antibody

MBS8512503-005mg 0.05mg
EUR 235

Cytochrome c Antibody

MBS8512503-01mg 0.1mg
EUR 305

Cytochrome c Antibody

MBS8512503-01mLAF405M 0.1mL(AF405M)
EUR 465

Cytochrome c Antibody

MBS8512503-01mLAF546 0.1mL(AF546)
EUR 465

Cytochrome c Antibody

MBS8512503-01mLAF750 0.1mL(AF750)
EUR 465

Cytochrome c Antibody

MBS8510641-005mg 0.05mg
EUR 235

Cytochrome c Antibody

MBS8510641-01mg 0.1mg
EUR 305

Cytochrome c Antibody

MBS8510641-01mLAF405M 0.1mL(AF405M)
EUR 465

Cytochrome c Antibody

MBS8510641-01mLAF546 0.1mL(AF546)
EUR 465

Cytochrome c Antibody

MBS8510641-01mLAF750 0.1mL(AF750)
EUR 465

Cytochrome C Antibody

MBS5315626-01mL 0.1mL
EUR 470

Cytochrome C Antibody

MBS5315626-5x01mL 5x0.1mL
EUR 1955

Cytochrome C Antibody

MBS5311127-01mg 0.1mg
EUR 545

Cytochrome C Antibody

MBS5311127-5x01mg 5x0.1mg
EUR 2400

Cytochrome C Antibody

MBS5311269-01mg 0.1mg
EUR 470

Cytochrome C Antibody

MBS5311269-5x01mg 5x0.1mg
EUR 2080

Cytochrome C Antibody

MBS5311270-01mg 0.1mg
EUR 470

Cytochrome C Antibody

MBS5311270-5x01mg 5x0.1mg
EUR 2080

Cytochrome C Antibody

MBS5312596-01mg 0.1mg
EUR 975

Cytochrome C Antibody

MBS5312596-5x01mg 5x0.1mg
EUR 4245

Cytochrome c Antibody

MBS9610366-005mL 0.05mL
EUR 245

Cytochrome c Antibody

MBS9610366-01mL 0.1mL
EUR 305

Cytochrome c Antibody

MBS9610366-02mL 0.2mL
EUR 365

Cytochrome c Antibody

MBS9610366-5x02mL 5x0.2mL
EUR 1495

Cytochrome C Antibody

MBS9435727-005mL 0.05mL
EUR 325

Cytochrome C Antibody

MBS9435727-01mL 0.1mL
EUR 435

Cytochrome C Antibody

MBS9435727-5x01mL 5x0.1mL
EUR 1810

Cytochrome C Antibody

MBS9435766-005mL 0.05mL
EUR 325

Cytochrome C Antibody

MBS9435766-01mL 0.1mL
EUR 435

Cytochrome C Antibody

MBS9435766-5x01mL 5x0.1mL
EUR 1810

Cytochrome c Antibody

MBS9504574-005mL 0.05mL
EUR 285

Cytochrome c Antibody

MBS9504574-01mL 0.1mL
EUR 385

Cytochrome c Antibody

MBS9504574-5x01mL 5x0.1mL
EUR 1590

Cytochrome c Antibody

MBS9600084-01mL 0.1mL
EUR 260

Cytochrome c Antibody

MBS9600084-02mL 0.2mL
EUR 305

Cytochrome c Antibody

MBS9600084-5x02mL 5x0.2mL
EUR 1220

Leave a Reply

Your email address will not be published.