Biology hyperlinks temporal protein adjustments to drug responses in a melanoma cell

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CCR2 of Tumor Microenvironmental Cells Is a Related Modulator of Glioma Biology

 Glioblastoma multiforme (GBM) reveals a excessive inflow of tumor-associated macrophages (TAMs). The CCR2/CCL2 pathway is taken into account a related sign for the recruitment of TAMs and has been urged as a therapeutic goal in malignant gliomas. We discovered that TAMs of human GBM specimens and of a syngeneic glioma mannequin specific CCR2 to various extents. 

Utilizing a Ccr2-deficient pressure for glioma inoculation revealed a 30% discount of TAMs intratumorally. This diminished immune cell infiltration occurred with augmented tumor volumes probably based mostly on elevated cell proliferation. Remaining TAMs in Ccr2-/- mice confirmed comparable floor marker expression patterns compared to wildtype mice, however expression ranges of inflammatory transcription components (Stat3Irf7Cox2) and cytokines (IfnβIl1βIl12α) had been significantly affected. 

Moreover, we demonstrated an impression on blood vessel integrity, whereas vascularization of tumors appeared related between mouse strains. The upper stability and attenuated leakiness of the tumor vasculature indicate improved sustenance of glioma tissue in Ccr2-/- mice. Moreover, regardless of TAMs residing within the perivascular area of interest in Ccr2-/- mice, their pro-angiogenic exercise was decreased by the downregulation of Vegf. In conclusion, missing CCR2 solely on tumor microenvironmental cells results in enhanced tumor development, whereby excessive numbers of TAMs infiltrate gliomas independently of the CCR2/CCL2 sign.

Perturbation biology hyperlinks temporal protein adjustments to drug responses in a melanoma cell line

Most cancers cells have genetic alterations that always immediately have an effect on intracellular protein signaling processes permitting them to bypass management mechanisms for cell dying, development and division. Most cancers medication focusing on these alterations usually work initially, however resistance is widespread. Combos of focused medication could overcome or forestall resistance, however their choice requires context-specific information of signaling pathways together with complicated interactions resembling suggestions loops and crosstalk.

To deduce quantitative pathway fashions, we collected a wealthy dataset on a melanoma cell line: Following perturbation with 54 drug combos, we measured 124 (phospho-)protein ranges and phenotypic response (cell development, apoptosis) in a time sequence from 10 minutes to 67 hours.

 From these knowledge, we educated time-resolved mathematical fashions that seize molecular interactions and the coupling of molecular ranges to mobile phenotype, which in flip reveal the primary direct or oblique molecular responses to every drug. Systematic mannequin simulations recognized novel combos of medication predicted to cut back the survival of melanoma cells, with partial experimental verification. This specific software of perturbation biology demonstrates the potential impression of mixing time-resolved knowledge with modeling for the invention of recent combos of most cancers medication. 

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biologiayctma

Rat Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

abx155155-50g 50 µg
EUR 687.5

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Ra 96T
EUR 499
Description: tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Ra-48T 48T
EUR 658.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Ra-96T 96T
EUR 861.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43280-48T 48T
EUR 410.83

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43280-5x96T 5x96T
EUR 2787.78

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43280-96T 96T
EUR 586.9

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02169-48T 48T
EUR 603.26

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02169-5x96T 5x96T
EUR 4093.55

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02169-96T 96T
EUR 861.8

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DL-ADRb1-Ra 96T
EUR 475
Description: tissue homogenates or other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EK12482 96Т
EUR 768

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-48T 48T
EUR 512.09
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-48Tests 48 Tests
EUR 699.6

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-96T 96T
EUR 731.54
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Ra-96Tests 96 Tests
EUR 973.2

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-10x96wellstestplate 10x96-wells test plate
EUR 6149.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-1x48wellstestplate 1x48-wells test plate
EUR 611.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-1x96wellstestplate 1x96-wells test plate
EUR 822.24
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

SEC924Ra-5x96wellstestplate 5x96-wells test plate
EUR 3340.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in tissue homogenates, cell lysates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

4-SEC924Ra
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-48T 48T
EUR 487.7
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-48Tests 48 Tests
EUR 668.4

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-96T 96T
EUR 696.7
Description: tissue homogenates and other biological fluids.

Rat Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RD-ADRb1-Ra-96Tests 96 Tests
EUR 930

Rat Adrb1/ Beta-1 adrenergic receptor ELISA Kit

E0033Ra 1 Kit
EUR 557
Description: Adrb1r,Beta-1 adrenoreceptor,Beta-1 adrenoceptor

Rat ADRb1(Adrenergic Receptor Beta 1) ELISA Kit

ELK7002-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADRb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADRb1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat ADRb1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat ADRb1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat ADRb1(Adrenergic Receptor Beta 1) ELISA Kit

ELK7002-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADRb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADRb1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat ADRb1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat ADRb1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat ADRb1(Adrenergic Receptor Beta 1) ELISA Kit

ER0719 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 46.875pg/ml

Rat Adrenergic Receptor Beta 1 ELISA Kit (ADRb1)

RK03473 96 Tests
EUR 625.2

ELISA kit for Rat Beta-1 adrenergic receptor (ADRB1)

KTE100346-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Rat Beta-1 adrenergic receptor (ADRB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Beta-1 adrenergic receptor (ADRB1)

KTE100346-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Rat Beta-1 adrenergic receptor (ADRB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Beta-1 adrenergic receptor (ADRB1)

KTE100346-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Rat Beta-1 adrenergic receptor (ADRB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Cow Beta-1 adrenergic receptor (ADRB1) ELISA Kit

abx515005-96tests 96 tests
EUR 1093.2

Dog Beta-1 adrenergic receptor (ADRB1) ELISA Kit

abx515006-96tests 96 tests
EUR 1093.2

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

abx515009-96tests 96 tests
EUR 1093.2

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24101PI-48Tests 48 Tests
EUR 360
Description: Pig (Sus scrofa; Porcine)

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24101PI-96Tests 96 Tests
EUR 680
Description: Pig (Sus scrofa; Porcine)

Pig Beta-1 adrenergic receptor (ADRB1) ELISA Kit

RK14988 96T
EUR 280

ADRb1 ELISA Kit| Rat Adrenergic Receptor Beta 1 ELISA Kit

EF017530 96 Tests
EUR 826.8

Human Beta- 1 adrenergic receptor, ADRB1 ELISA KIT

ELI-49531h 96 Tests
EUR 988.8

Mouse Beta- 1 adrenergic receptor, Adrb1 ELISA KIT

ELI-24563m 96 Tests
EUR 1038

Bovine Beta- 1 adrenergic receptor, ADRB1 ELISA KIT

ELI-49530b 96 Tests
EUR 1113.6

Mouse Beta-1 adrenergic receptor(ADRB1) Elisa kit

EK732043 96 Wells
EUR 0.84

Mouse Beta-1 adrenergic receptor (ADRB1) ELISA Kit

EK7760 96Т
EUR 799

Human Beta-1 adrenergic receptor(ADRB1) Elisa Kit

EK714655 96 Wells
EUR 0.48

Human Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

abx515007-96tests 96 tests
EUR 801.6

Mouse Beta-1 adrenergic receptor (ADRB1) ELISA Kit

abx571427-96tests 96 tests
EUR 886.8

Human Beta-1 adrenergic receptor(ADRB1) ELISA kit

CSB-EL001391HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Beta-1 adrenergic receptor (ADRB1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Beta-1 adrenergic receptor(ADRB1) ELISA kit

1-CSB-EL001391HU
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  • Ask for price
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Beta-1 adrenergic receptor(ADRB1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24098HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24098HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Mouse Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24100MO-48Tests 48 Tests
EUR 325
Description: Mouse (Mus musculus)

Mouse Beta-1 adrenergic receptor (ADRB1) ELISA Kit

AE24100MO-96Tests 96 Tests
EUR 610
Description: Mouse (Mus musculus)

Mouse Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

20-abx153603
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

20-abx156917
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  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit

KTE60949-48T 48T
EUR 339
Description: This Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit employs a two-site sandwich ELISA to quantitate ADRB1.

Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit

KTE60949-96T 96T
EUR 589
Description: This Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit employs a two-site sandwich ELISA to quantitate ADRB1.

Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit

KTE60949-96T5 96 T×5
EUR 2629
Description: This Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit employs a two-site sandwich ELISA to quantitate ADRB1.

Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit

KTE60949-96T50 96 T×50
EUR 24569
Description: This Human Beta-1 adrenergic receptor (ADRB1) ELISA Kit employs a two-site sandwich ELISA to quantitate ADRB1.

Mouse Beta-1 adrenergic receptor (ADRB1) ELISA Kit

RK12527 96T
EUR 280

Human Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

abx156917-100g 100 µg
EUR 5575

Human Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

abx156917-10g 10 µg
EUR 618.75

Human Beta-1 Adrenergic Receptor (ADRB1) ELISA Kit

abx156917-50g 50 µg
EUR 2950

Porcine Beta- 1 adrenergic receptor, ADRB1 ELISA KIT

ELI-24819p 96 Tests
EUR 1113.6

ELISA kit for Rat ADRb1 (Adrenergic Receptor Beta 1)

ELK7002 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Adrenergic Receptor Beta 1 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Canine Beta-1 adrenergic receptor, ADRB1 ELISA KIT

ELI-34655d 96 Tests
EUR 1113.6

Rat Beta-1 adrenergic Receptor, ADRB1 GENLISA ELISA

KLR1882 1 x 96 wells
EUR 341

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Hu 96T
EUR 463
Description: serum, plasma, tissue homogenates or other biological fluids.

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Adrenergic Receptor Beta 1 (ADRb1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Adrenergic Receptor Beta 1 (ADRb1) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Mu 96T
EUR 475
Description: tissue homogenates or other biological fluids.

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates or other biological fluids.

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DLR-ADRb1-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Adrenergic Receptor Beta 1 (ADRb1) in samples from tissue homogenates or other biological fluids.

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43279-48T 48T
EUR 389.62

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43279-5x96T 5x96T
EUR 2643.85

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN43279-96T 96T
EUR 556.6

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU09143-48T 48T
EUR 555.66

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU09143-5x96T 5x96T
EUR 3770.55

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU09143-96T 96T
EUR 793.8

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02168-48T 48T
EUR 571.55

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02168-5x96T 5x96T
EUR 3878.38

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKU02168-96T 96T
EUR 816.5

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKL55297-5x96T 5x96T
EUR 3793.35

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKL55297-96T 96T
EUR 798.6

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN50254-48T 48T
EUR 345.73

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN50254-5x96T 5x96T
EUR 2346.03

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EKN50254-96T 96T
EUR 493.9

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DL-ADRb1-Hu 96T
EUR 441
Description: serum, plasma, tissue homogenates or other biological fluids.

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

DL-ADRb1-Mu 96T
EUR 453
Description: tissue homogenates or other biological fluids.

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EK12480 96Т
EUR 768

Mouse Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

EK12481 96Т
EUR 768

Human Adrenergic Receptor Beta 1 (ADRb1) ELISA Kit

RDR-ADRb1-Hu-48T 48T
EUR 475.34
Description: serum, plasma, tissue homogenates and other biological fluids.

On the leading edge: protease-based strategies for sensing and controlling cell biology

Sequence-specific proteases have confirmed to be versatile constructing blocks for instruments that report or management mobile perform. Reporting strategies hyperlink protease exercise to biochemical alerts, whereas management strategies depend on engineering proteases to reply to exogenous inputs resembling gentle or chemical substances.

 In flip, proteases have inherent management skills, as their native features are to launch, activate or destroy proteins by cleavage, with the irreversibility of proteolysis permitting sustained downstream results. In consequence, protease-based artificial circuits have been created for various makes use of resembling reporting mobile signaling, tuning protein expression, controlling viral replication and detecting most cancers states. Right here, we comprehensively evaluate the event and software of protease-based strategies for reporting and controlling mobile perform in eukaryotes. 

Cytochrome C Antibody

21680-100ul 100ul
EUR 302.4

Cytochrome C Antibody

21680-50ul 50ul
EUR 224.4

Cytochrome c antibody

20R-1430 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

20R-1518 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

20R-1519 100 ug
EUR 807.6
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c Antibody

3025-100 each
EUR 438

Cytochrome c Antibody

3025-30T each
EUR 175.2

Cytochrome c Antibody

33354 100ul
EUR 319

Cytochrome c Antibody

33354-100ul 100ul
EUR 302.4

Cytochrome c Antibody

33354-50ul 50ul
EUR 224.4

Cytochrome c Antibody

3352-100 each
EUR 379.2

Cytochrome c Antibody

3352-30T each
EUR 175.2

Cytochrome c Antibody

3353-100 each
EUR 379.2

Cytochrome c Antibody

3353-30T each
EUR 175.2

Cytochrome C Antibody

48927 100ul
EUR 499

Cytochrome C Antibody

48927-100ul 100ul
EUR 399.6

Cytochrome C Antibody

48927-50ul 50ul
EUR 286.8

Cytochrome C Antibody

48976 100ul
EUR 499

Cytochrome C Antibody

48976-100ul 100ul
EUR 399.6

Cytochrome C Antibody

48976-50ul 50ul
EUR 286.8

Cytochrome c Antibody

E033354 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cytochrome C Antibody

E021680 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Cytochrome c Antibody

E11-0170C 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-0146-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-0146-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-7004-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Cytochrome c Antibody

E18-7004-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Cytochrome C Antibody

DF6028 200ul
EUR 420

Cytochrome C Antibody

DF6028-100ul 100ul
EUR 280

Cytochrome C Antibody

DF6028-200ul 200ul
EUR 350

Cytochrome c Antibody

E38PA6018 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E38PA9145 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c Antibody

E38PA2689 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome C antibody

BF0714 200ul
EUR 540

Cytochrome C antibody

BF0714-100ul 100ul
EUR 350

Cytochrome C antibody

BF0714-200ul 200ul
EUR 450

Cytochrome C antibody

BF0714-50ul 50ul
EUR 250

Cytochrome c antibody

70R-13781 100 ug
EUR 519
Description: Affinity purified Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11564 100 ug
EUR 406
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11766 100 ug
EUR 343
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome c antibody

70R-11767 100 ug
EUR 343
Description: Rabbit polyclonal Cytochrome c antibody

Cytochrome C antibody

70R-31158 100 ug
EUR 294
Description: Rabbit polyclonal Cytochrome C antibody

Cytochrome C antibody

70R-51008 100 ul
EUR 242
Description: Purified Polyclonal Cytochrome C antibody

Cytochrome C Antibody

AF0146 200ul
EUR 420

Cytochrome C Antibody

AF0146-100ul 100ul
EUR 280

Cytochrome C Antibody

AF0146-200ul 200ul
EUR 350

Cytochrome C Antibody

AF7004 200ul
EUR 540

Cytochrome C Antibody

AF7004-100ul 100ul
EUR 350

Cytochrome C Antibody

AF7004-200ul 200ul
EUR 450

Cytochrome C Antibody

AF7004-50ul 50ul
EUR 250

Cytochrome c Antibody

ABF7004 100 ug
EUR 525.6

Cytochrome c Antibody

ABF0146 100 ug
EUR 525.6

Cytochrome C Antibody

GWB-56035A 0.1 mg Ask for price

Cytochrome C, Antibody

GWB-5AC847 1 ml Ask for price

Cytochrome C, Antibody

GWB-83C84A 7 ml Ask for price

Cytochrome C Antibody

GWB-F62EAD 0.1 mg Ask for price

Cytochrome C Antibody

GWB-CE42EA 0.05 mg Ask for price

Cytochrome c antibody

PAab098271 100 ug
EUR 463.2

Cytochrome C Antibody

R32947 100 ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

R31747 100 ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

RQ4499 100ug
EUR 356.15
Description: CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Cytochrome C Antibody

V8015-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8015-20UG 20 ug
EUR 153.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8015SAF-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358-20UG 20 ug
EUR 153.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V8358SAF-100UG 100 ug
EUR 349.3
Description: In mammalian cells, the highly conserved cytochrome C protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e. cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2785-100UG 100 ug
EUR 424.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2785-20UG 20 ug
EUR 186.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2785SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome c is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2786-100UG 100 ug
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786-20UG 20 ug
EUR 186.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786IHC-7ML 7 ml
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2786SAF-100UG 100 ug
EUR 424.15
Description: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2787SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody

V2788-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2788SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Cytochrome C Antibody

V2789-100UG 100 ug
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789-20UG 20 ug
EUR 186.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

Cytochrome C Antibody

V2789SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C, or CYCS, is an electron carrier protein. The oxidized form of the CYCS heme group can accept an electron from the heme group of the Cytochrome C1 subunit of cytochrome reductase. CYCS then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; CYCS also plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of CYCS into the cytosol. Binding to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. [UniProt]

anti- Cytochrome b5 antibody

FNab02186 100µg
EUR 606.3
Description: Antibody raised against Cytochrome b5

Cytochrome C antibody (FITC)

61R-1166 100 ug
EUR 564
Description: Mouse monoclonal Cytochrome C antibody (FITC)

Cytochrome C Antibody Cocktail

V2790-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody Cocktail

V2790-20UG 20 ug
EUR 186.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody Cocktail

V2790IHC-7ML 7 ml
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Cytochrome C Antibody Cocktail

V2790SAF-100UG 100 ug
EUR 424.15
Description: Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This mAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).

Rabbit anti Cytochrome C Polyclonal Antibody

TA354160 100 µg Ask for price

Polyclonal Cytochrome c Antibody

APR00077G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cytochrome c . This antibody is tested and proven to work in the following applications:

Polyclonal Cytochrome c Antibody

APR07477G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cytochrome c . This antibody is tested and proven to work in the following applications:

Cytochrome C IHC Antibody

IW-PA1118 -
EUR 285

Cytochrome C (CYCS) Antibody

20-abx134056
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Cytochrome C (CYCS) Antibody

20-abx008130
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Cytochrome C (CYCS) Antibody

20-abx013057
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  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Cytochrome C (CYCS) Antibody

abx232187-100ug 100 ug
EUR 610.8

Cytochrome c(cycs)Antibody

E90051 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome C (CYCS) Antibody

abx013057-100g 100 µg
EUR 237.5

Cytochrome C (CYCS) Antibody

abx013057-10g 10 µg
EUR 43.75

Cytochrome C (CYCS) Antibody

abx013057-200g 200 µg
EUR 312.5

Cytochrome C (CYCS) Antibody

abx239884-100l 100 µl Ask for price

Cytochrome C (CYCS) Antibody

abx239884-50l 50 µl
EUR 350

Cytochrome C (CYCS) Antibody

abx232187-100g 100 µg
EUR 350

Cytochrome C(CTC05) Antibody

BNC810887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), CF680R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC810887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), CF680R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC800887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), CF680 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC800887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), CF680 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC430887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), CF543 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC430887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), CF543 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC050887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), CF405M conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC050887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), CF405M conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC700887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), CF770 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC700887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), CF770 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC610887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), CF660R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNC610887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), CF660R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNCP0887-250 250uL
EUR 459.6
Description: Primary antibody against Cytochrome C(CTC05), PerCP conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNCR0887-250 250uL
EUR 459.6
Description: Primary antibody against Cytochrome C(CTC05), RPE conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNCA0887-250 250uL
EUR 459.6
Description: Primary antibody against Cytochrome C(CTC05), APC conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNCAP0887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNCAP0887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNCH0887-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CTC05), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytochrome C(CTC05) Antibody

BNCH0887-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CTC05), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytochrome c Antibody (Clone 7H8.2C12)

3026-50 each
EUR 535.2

Cytochrome C(CYCS/1010) Antibody

BNC811010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF680R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC811010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF680R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC801010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF680 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC801010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF680 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC431010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF543 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC431010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF543 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC051010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF405M conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC051010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF405M conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC551010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF555 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC551010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF555 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC701010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF770 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC701010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF770 conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC611010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF660R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNC611010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), CF660R conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNCP1010-250 250uL
EUR 459.6
Description: Primary antibody against Cytochrome C(CYCS/1010), PerCP conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNCR1010-250 250uL
EUR 459.6
Description: Primary antibody against Cytochrome C(CYCS/1010), RPE conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNCA1010-250 250uL
EUR 459.6
Description: Primary antibody against Cytochrome C(CYCS/1010), APC conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNCAP1010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNCAP1010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNCH1010-100 100uL
EUR 238.8
Description: Primary antibody against Cytochrome C(CYCS/1010), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Cytochrome C(CYCS/1010) Antibody

BNCH1010-500 500uL
EUR 652.8
Description: Primary antibody against Cytochrome C(CYCS/1010), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Mouse Anti Human Cytochrome C Monoclonal Antibody

CABT-49976MH 0.1 mg
EUR 982.8

Cytochrome c Polyclonal Antibody

29153 100ul
EUR 439

Cytochrome c Polyclonal Antibody

42140 100μg
EUR 390

Cytochrome c Polyclonal Antibody

42140-100ul 100ul
EUR 399.6

Cytochrome c polyclonal antibody

E43AS75125 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome c Polyclonal Antibody

E913430a 100ul
EUR 225
Description: Available in various conjugation types.

Cytochrome C Conjugated Antibody

C21680 100ul
EUR 476.4

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